ArticleSubstance abuse and rehabilitation2026
Treatment Outcomes in a Specialized Opioid Maintenance Program for Prescription Opioid Use Disorder in Israel.
Article in Substance abuse and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Trauma History Among Patients Receiving Methadone Maintenance Treatment: Sex Differences, Characteristics, and Outcomes.Substance abuse and rehabilitation · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: A rapid increase in opioid prescriptions necessitated the implementation of a specific opioid maintenance treatment arm in the Methadone Maintenance Treatment clinic for opioid use disorder (OUD). Objective: To characterize patients referred to this arm, those who initiated treatment and their outcomes. Methods: Individuals referred between November/2019 and June/2025 were included. Patient characteristics, retention, and drug abstinence were studied. Results: Of 184 referrals, 54 (29.3%) were admitted. They had a higher female proportion (50% vs. 32.3%, p=0.03) and more years of education (13.1±3.4 vs. 11.2±3.8, p=0.008) than those not admitted, with no significant age difference (50.5±15.8 vs. 52.0±16.4, p=0.6). Of the 54 admitted patients, 5 were transferred to the "regular" OUD arm. Of the remaining 49, 18.4% were treated with methadone and 40 with oral buprenorphine (21 switched later to a once-monthly injectable formulation). Overall, 42.9% used fentanyl: 44.4% of those on methadone, 42.1% on buprenorphine, and 42.9% on the injectable formulation. Ninety (51.4%) stayed one year; of them, 88.9% stopped prescription opioids. Cumulative retention was longer among females (2.3y, 95% CI: 1.8-2.9) than males (1.2y, 95% CI: 0.8-1.6, p=0.046). Retention among those treated with injectable buprenorphine (2.4y, 95% CI: 1.8-3.0) or methadone (1.7y, 95% CI: 0.9-2.4) was comparable, and both were longer than with oral buprenorphine (0.7y, 95% CI: 0.4-1.0, p<0.001 and p=0.039, respectively). Conclusion: Positive treatment outcomes were observed in this specific population, particularly among those treated with methadone or injectable buprenorphine, but future follow-up and a larger sample are needed. Physicians' education is necessary to achieve more accurate referrals.
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