ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2026
Blood Urea Nitrogen to Albumin Ratio is Associated with Diabetic Peripheral Neuropathy in Patients with Type 2 Diabetes Mellitus.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Blood urea nitrogen (BUN) to albumin ratio (BAR) serves as a multifaceted parameter indicative of inflammatory, renal, endothelial, and nutritional functions. Previous studies have demonstrated that an elevated BAR is a valuable biomarker with predictive significance in various diseases. Nonetheless, the association between BAR and diabetic peripheral neuropathy (DPN) has not been previously documented. This study seeks to explore the potential association between BAR and DPN in patients with type 2 diabetes mellitus (T2DM). Patients and Methods: A total of 3239 patients diagnosed with T2DM admitted to the Second Affiliated Hospital of Wenzhou Medical University from 2018 to 2023 were included in this cross-sectional study. The analysis was conducted through logistic regression and restricted cubic spline (RCS) methodologies, complemented by additional stratified and interaction analyses. Results: As the quartiles of BAR increased, there was a notable increase in the prevalence of DPN, with the rates of 13.3%, 19.4%, 26.0%, and 38.3%, respectively. Logistic regression analysis showed a positive association between BAR and DPN (OR=1.20, 95% CI: 1.12-1.28), which was consistently observed across all subgroups through stratified analysis. RCS analysis identified a linear association, without saturation effects. Additionally, AUC for BAR (AUC = 0.660, 95% CI: 0.639-0.683) was significantly higher compared to those of BUN and albumin alone. Conclusion: BAR exhibits a positive association with the risk of DPN, underscoring its potential utility as a cost-effective biomarker for stratifying the risk of DPN.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.