ArticleWorld journal of clinical pediatrics2026
Efficacy of vitamin D supplementation for children with acute bronchiolitis: A randomized controlled trial.
Article in World journal of clinical pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPrevious studies have suggested an association between vitamin D deficiency and bronchiolitis, but the therapeutic benefits of vitamin D supplementation remain uncertain.
aimTo investigate the efficacy of vitamin D supplementation for hospitalized children with acute bronchiolitis.
methodsThis two-arm randomized controlled trial included 146 children aged 3-24 months who were hospitalized with bronchiolitis at an Egyptian tertiary care center. Participants were equally randomized to receive a single intramuscular dose of 200000 IU (study group) or a daily oral dose of 400 IU (comparison group) of vitamin D
resultsIn the overall analysis, the study and comparison groups showed no significant differences in median time to discharge (130 hours
conclusionVitamin D supplementation may improve clinical outcomes in hospitalized children with bronchiolitis who have vitamin D deficiency or insufficiency, supporting a test-and-treat approach.
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