Evidence map›Paper›PMID 41883904›Full record

ArticleCureus2026

The Immediate Effect of Cold Spinal Spray and Cold Spinal Bath on Cognition Among Young Adults: A Three-Armed Randomized Controlled Trial.

Avishee Sinha, Sujatha Kj

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In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Avishee SinhaNatural Therapeutics, Shri Dharmasthala Manjunatheshwara (SDM) College of Naturopathy and Yogic Sciences, Ujire, IND.
Sujatha KjNatural Therapeutics, Shri Dharmasthala Manjunatheshwara (SDM) College of Naturopathy and Yogic Sciences, Ujire, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Cognition is a complex process that involves acquiring knowledge and understanding. Hydrotherapy, a part of naturopathy, particularly cold spinal spray and cold spinal bath, is used to influence physiological responses. However, its immediate effects on cognition remain unexplored. This study aims to evaluate the immediate effect of cold spinal spray and cold spinal bath on cognition among young adults using a three-armed randomized controlled trial. Methods A total of 90 healthy volunteers (aged 18-25 years) were recruited and randomly assigned into three groups: group 1 - cold spinal spray (n=30), group 2 - cold spinal bath (n=30), and group 3 - control group (n=30). Interventions were administered for 15 minutes. Cognitive assessments were conducted pre- and post-intervention using the Stroop test and Letter-Digit Substitution Test (LDST). Heart rate variability (HRV) was measured as a secondary outcome. Data were analyzed using Jamovi version 2.7.6 statistical software (the Jamovi Project, Sydney, Australia). Results Both cold spinal spray and cold spinal bath groups demonstrated statistically significant improvements in cognitive performance, including increased accuracy and reduced error rates, compared with the control group (p<0.05), with large effect sizes observed for primary cognitive outcomes (η²≥0.14). The cold spinal spray group exhibited a more pronounced improvement in cognitive scores compared to the cold spinal bath group. HRV analysis showed enhanced autonomic regulation post-intervention most in the cold spinal spray group. Conclusion Cold spinal spray and cold spinal bath have an immediate positive effect on cognitive functions, with cold spinal spray demonstrating a slightly greater impact. These findings suggest the potential of hydrotherapy in enhancing cognition and the scope of these applications to patients with cognitive decline.

Indexed as

autonomic functioncognitive functioncold spinal bathcold spinal sprayheart rate variability (hrv)hydrotherapymental cognitionnaturopathyrandomized controlled trial (rct)vagus nerve stimulation

Identifiers

PMID41883904
PMCPMC13009221

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.