Evidence map›Paper›PMID 41883793›Full record

ArticleFrontiers in microbiology2026

Culture-based studies of intestinal lactobacilli in young people and centenarians.

Imbi Smidt, Tiiu Roop, Reet Mandar, Jelena Stsepetova, Siiri Koljalg, Kalle Kilk, Indrek Soidla, Mare Ainsaar, Helgi Kolk, Epp Sepp

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In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Imbi SmidtDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Tiiu RoopDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Reet MandarDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Jelena StsepetovaDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Siiri KoljalgDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Kalle KilkDepartment of Biochemistry, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Indrek SoidlaFaculty of Social Sciences, Institute of Social Studies, University of Tartu, Tartu, Estonia.
Mare AinsaarFaculty of Social Sciences, Institute of Social Studies, University of Tartu, Tartu, Estonia.
Helgi KolkDepartment of Internal Medicine, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Epp SeppDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Biological ageing is associated with physiological changes, including alterations in the gut microbiota. Lactobacilli may contribute to host health and longevity, yet their composition and functional properties in centenarians remain poorly characterized. The present study aimed to compare cultured intestinal lactobacilli from centenarians and young adults and to identify strains with potential probiotic properties. Methods: Fecal samples were obtained from centenarians ( Results: Twenty Discussion: Lactobacilli isolated from centenarian demonstrate distinct compositional and metabolic characteristics compared with those from young adults. These differences may reflect functional adaptations potentially relevant to healthy ageing and could inform the selection of candidate strains for future probiotic development.

Indexed as

biochemical profilecentenarianslactobacillimetabolic activitiesmicrobiotaprobiotics

Identifiers

PMID41883793
PMCPMC13008948

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.