Evidence map›Paper›PMID 41883743›Full record

ArticleAlzheimer's & dementia. Behavior & socioeconomics of aging2025

Protocol for assessing urban-rural environmental stress disparities in ADRD through ecological momentary assessment (AURESIA).

Sarah A Greenwell, Laurel S Curran, Chasie E Poe, Maria Klein, Xing Yao, Bailey K Ortyl, Patrick C Shih, Erik J Nelson, Malaz Boustani, Paul Dexter and 5 more

Abstract read
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In one paragraph

Article in Alzheimer's & dementia. Behavior & socioeconomics of aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sarah A GreenwellDepartment of Health & Wellness Design, Indiana University School of Public Health, Bloomington, Indiana, USA.
Laurel S CurranDepartment of Health & Wellness Design, Indiana University School of Public Health, Bloomington, Indiana, USA.
Chasie E PoeDepartment of Health & Wellness Design, Indiana University School of Public Health, Bloomington, Indiana, USA.
Maria KleinDepartment of Epidemiology and Biostatistics, Indiana University, Bloomington, Indiana, USA.
Xing YaoDepartment of Health & Wellness Design, Indiana University School of Public Health, Bloomington, Indiana, USA.
Bailey K OrtylDepartment of Epidemiology and Biostatistics, Indiana University, Bloomington, Indiana, USA.
Patrick C ShihLuddy School of Informatics, Computing, and Engineering, Indiana University, Bloomington, Indiana, USA.
Erik J NelsonDepartment of Public Health, Brigham Young University, Provo, Utah, USA.
Malaz BoustaniRegenstrief Institute, Inc., Indianapolis, Indiana, USA.
Paul DexterRegenstrief Institute, Inc., Indianapolis, Indiana, USA.
Zina Ben MiledPhillip M Drayer Department of Electrical and Computer Engineering, Lamar University, Beaumont, Texas, USA.
Mario SchootmanCollege of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Stephanie DickinsonDepartment of Epidemiology and Biostatistics, Indiana University, Bloomington, Indiana, USA.
Frederick W UnverzagtDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Evan J JordanDepartment of Health & Wellness Design, Indiana University School of Public Health, Bloomington, Indiana, USA.

Funding

Assessing Urban-Rural Environmental Stress Inequities in ADRD through Ecological Momentary AssessmentR01NS139192 · NINDS · TRUSTEES OF INDIANA UNIVERSITY · PI Evan Jordan · 2024 to 2026
$2.3M
NINDS NIH HHS R01 NS139192
6 · The paper itself

Abstract

Introduction: Consistent exposure to environmental stressors increases the risk of Alzheimer's disease and related dementias (ADRD). Little is known about the timing, location, and nature of these stressors. We outline the protocol for an ongoing study using a novel ecological momentary assessment app to evaluate environmental stressors in urban and rural adults with mild cognitive impairment (MCI). Methods: We assess cognitive status at baseline and follow-up appointments for 2 years. During a 2-week stress-reporting period, participants self-report environmental stressors. We monitor physiological data via Smartwatch. The app collects geospatial data, which we analyze via spatiotemporal regression models. Results: The study will take 3 years to complete. Discussion: This study will advance knowledge of when, where, and what stressors occur among older adults and will underscore targets for intervention at individual and neighborhood levels to prevent progression from MCI to ADRD and reduce urban-rural disparities in older adults.

Indexed as

Alzheimer’s disease and related dementiasecological momentary assessmentenvironmental stressgeospatial analysis

Identifiers

PMID41883743
PMCPMC13010532

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.