ReviewFrontiers in microbiomes2025
Intestinal dysbiosis during pregnancy and microbiota-associated impairments in offspring.
Review in Frontiers in microbiomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Gut microbiome and pregnancy complications: emerging evidence and mechanistic insights.Gut microbes · 2026Review
- Insights into Microbiota-Vaccine Crosstalk in Humans: Mechanisms, Modulators, and Translational Horizons.Vaccines · 2026Review
- Maternal Diet During Pregnancy and Offspring Health: Current Evidence on Dietary Patterns, Microbiota, and Developmental Programming.Nutrients · 2026Review
- Unhealthy Diets, Unhealthy Futures: How Modern Eating Patterns Endanger Maternal and Offspring Health.Nutrients · 2026Review
- Gestational dysbiosis is associated with altered early-life microbial seeding and favors pathobiont expansion in offspring.iScience · 2026Article
- Perinatal Antibiotic Timing Impairs Maternal IgG Transfer via FcRn and Shapes the Neonatal Gut Microbiome in Mice.Microorganisms · 2026Article
- The maternal-infant microbiome axis as an epigenetic and immunometabolic orchestrator: redefining early-life programming and precision interventions for lifelong women's and children's health.Infection and immunity · 2026Review
- Maternal obesity, diet, and the gut microbiome: implications for offspring cardiometabolic programming.Frontiers in nutrition · 2026Review
- Gut and Gastric Dysbiosis in Hyperemesis Gravidarum: A Scoping Review of Microbiome-Targeted Evidence and Translational Pathways.International journal of women's health · 2026Review
- Breastfeeding in a Polluted World: Perspective on the Properties of Breast Milk and the Need for Protection.Journal of clinical medicine · 2025Article
- Maternal Euglena gracilis supplementation alters sow and piglet gut microbiota, reduces diarrhea incidence, and enhances piglet growth.Animal microbiome · 2025Article
- Microbial dysbiosis and associated disease mechanisms in maternal and child health.Infection and immunity · 2025Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The maternal microbiome is increasingly being recognized as a key determinant in various neonatal health outcomes, including offspring immunity, metabolism, brain function, and behavior. While the oral, vaginal, skin, and gut microbiota are significant contributors to the offspring's postnatal gut microbial seeding, the composition and diversity of the maternal gut microbiome during pregnancy seems to be critical in shaping neonatal health outcomes, even prior to birth. Growing evidence suggests that the balance among the microbial groups in the gut and their interactions with the host are crucial for health. Dysbiotic communities in pregnancy and early in life may lead to disease processes in offspring, though the specific processes by which maternal gut microbes affect offspring gut microbial development are unknown. Here, we summarize research examining gut microbial shifts during pregnancy, and their effects on the diversity and composition of the infant microbiome and on early health outcomes. We also discuss current theories for how the maternal gastrointestinal (GI) tract influences neonatal seeding, and how probiotics during the perinatal period may affect offspring health outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.