Evidence map›Paper›PMID 41883715›Full record

ArticleCancer informatics2026

hsa-miR-1246 is Consistently Overexpressed in Spheroid-Derived Cancer Stem Cells From Multiple Tumor Types.

Ángela Y García Fonseca, Yeimy González-Giraldo, Natalia Vargas Rondón, Andrés F Aristizábal-Pachón

Abstract read
In one paragraph

Article in Cancer informatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ángela Y García FonsecaDepartamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, DC, Colombia.ORCID https://orcid.org/0000-0001-7502-5542
Yeimy González-GiraldoDepartamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, DC, Colombia.
Natalia Vargas RondónDepartamento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, DC, Colombia.
Andrés F Aristizábal-PachónFoundation for Applied Clinical and Molecular Cancer Research - FICMAC, Bogotá, DC, Colombia.ORCID https://orcid.org/0000-0003-3004-4867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumors consist of various cell types, including a small population of cancer stem cells (CSCs), which are linked to metastasis, drug resistance, and recurrence. Maintaining the CSC phenotype requires regulation of molecules, including miRNAs; they are small non-coding RNAs involved in processes such as proliferation, differentiation, invasion, and apoptosis. However, miRNAs involved in CSC generation and maintenance remain largely unidentified. In this study, we aimed to identify miRNAs associated with CSC populations by studying the miRNA profiles in Spheroids-Derived cancer stem cells (SDCSCs) from different cancer cell lines. Firstly, we used small RNA sequencing by Illumina to identify differentially expressed miRNAs from SDCSCs compared with adherent cells from lung cancer cell line. MiRNAs with

Indexed as

cancer stem cellscellular heterogeneitymiRNAstumor plasticity

Identifiers

PMID41883715
PMCPMC13009628

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.