ReviewFrontiers in pain research (Lausanne, Switzerland)2026
Impact of therapeutic exercises on pain-related outcomes in patients with knee osteoarthritis: an umbrella review of 116 systematic reviews.
Review in Frontiers in pain research (Lausanne, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Effects of a Cycling-Based Aerobic Exercise Program Versus a Resistance and Neuromuscular Exercise Program on Exercise-Induced Hypoalgesia in Knee Osteoarthritis: A Study Protocol for a Randomized Clinical Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Article
- Genicular Artery Embolization for Chronic Exudative Knee Synovitis: Prospective 6-Month Clinical and Functional Outcomes.Journal of clinical medicine · 2026Article
- From paradox to population impact: Rethinking strengthening in knee osteoarthritis - A state-of-the-art review.Osteoarthritis and cartilage open · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and objectives: Chronic knee pain is highly prevalent in various knee diseases. It significantly decreases patients' quality of life. Among non-surgical interventions, exercise is considered a promising approach for alleviating chronic knee pain. This umbrella review aimed to systematically synthesize and critically appraise evidence from recent systematic reviews on the effectiveness of therapeutic exercises for knee osteoarthritis across pain, physical function, quality of life, and biomechanical outcomes. Materials and methods: We searched for systematic reviews with/without meta-analyses in PubMed, Scopus, and Cochrane Library databases. Results: A total of 116 systematic reviews and meta-analyses were included, published predominantly after 2014. Interrater agreement was substantial ( Conclusions: Therapeutic exercises may help reduce pain, improve physical function and quality of life in patients with knee osteoarthritis. However, the overall certainty of evidence is limited by the variable methodological quality of the included systematic reviews. At present, no single type of therapeutic exercise can be considered the most effective for all individuals with knee osteoarthritis. Systematic Review Registration: https://osf.io/pqgrv/overview, doi: 10.17605/OSF.IO/PQGRV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.