Evidence map›Paper›PMID 41883691›Full record

ArticleFrontiers in neuroanatomy2026

Age-related dopaminergic integrity in the SNpc and VTA: morphometric and volumetric findings in marmoset (

Maria M O Azambuja, Nelyane N M de Santana, Paulo L A G Morais, Gabriel A M Vasiljevic, Jeferson S Cavalcante, Adhil Bhagwandin, José R L P Cavalcanti, Rovena Clara Engelberth

Abstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Maria M O Azambuja *Laboratory of Neurochemical Studies, Department of Physiology and Behavior, Bioscience Center, Federal University of Rio Grande do Norte, Natal, Brazil.
Nelyane N M de Santana *Laboratory of Experimental Neurology, College of the Health Sciences, State University of Rio Grande do Norte, Mossoró, Brazil.
Paulo L A G Morais *Laboratory of Neurochemical Studies, Department of Physiology and Behavior, Bioscience Center, Federal University of Rio Grande do Norte, Natal, Brazil.
Gabriel A M VasiljevicEdmond and Lily Safra International Institute of Neuroscience, Santos Dumont Institute, Macaíba, Brazil.
Jeferson S CavalcanteLaboratory of Neurochemical Studies, Department of Physiology and Behavior, Bioscience Center, Federal University of Rio Grande do Norte, Natal, Brazil.
Adhil BhagwandinDivision of Clinical Anatomy and Biological Anthropology Department of Human Biology, Faculty of Health Sciences University of Cape Town, Cape Town, South Africa.
José R L P CavalcantiLaboratory of Experimental Neurology, College of the Health Sciences, State University of Rio Grande do Norte, Mossoró, Brazil.
Rovena Clara EngelberthLaboratory of Neurochemical Studies, Department of Physiology and Behavior, Bioscience Center, Federal University of Rio Grande do Norte, Natal, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given a convergence of evidence indicating age-related vulnerability in nuclei associated with basal ganglia circuits, understanding the pattern of normal aging in non-human primates is essential for basic and applied research. To address this, we examined the age-dependent vulnerability of dopaminergic cells in the substantia nigra pars compacta (SNpc) and ventral tegmental area (VTA) of marmoset through morphoquantitative analysis of cytoarchitecture. Thus, we selected brain tissue from adult and aged marmosets processed for tyrosine hydroxylase (TH) immunohistochemistry. We estimated regional volume and counted TH-immunopositive (TH

Indexed as

agingdopaminmarmosetsubstantia nigratyrosine hydroxylaseventral tegmental area

Identifiers

PMID41883691
PMCPMC13008971

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