Evidence map›Paper›PMID 41883626›Full record

ArticleInfection prevention in practice2026

Effect of bathing with 2% chlorhexidine gluconate every other day on healthcare-associated infections in the medical intensive care unit.

Shu-Fen Hsu, Pei-Jung Yu, Hsing-Yu Yang, Te-Yu Wu

Abstract read
In one paragraph

Article in Infection prevention in practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Does alternate-day bathing with 2% chlorhexidine improve clinical outcomes in critically ill patients? A systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shu-Fen HsuDepartment of Nursing, MacKay Memorial Hospital, Taipei City, Taiwan.
Pei-Jung YuSchool of Nursing, MacKay Medical University, Taipei City, Taiwan.
Hsing-Yu YangSchool of Nursing, MacKay Medical University, Taipei City, Taiwan.
Te-Yu WuDepartment of Nursing, MacKay Memorial Hospital, Taipei City, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Healthcare-associated infections (HAIs) cause morbidity and mortality in patients at medical intensive care units (MICUs). However, current literature reports inconsistent findings on the effect of daily bathing with 2% chlorhexidine gluconate (CHG) on reducing HAIs and that the solution can cause skin harm. This study aimed to explore the effect of bathing with 2% CHG every 2 days on HAIs in the MICU. Methods: This study used a quasi-experimental design (experimental group) and a medical record review (control group). Patients in the control group were admitted to the MICU at a medical centre in Taiwan from March 2018 to February 2019 and used general soap for bathing every other day as part of the unit's routine. The experimental group was recruited from March 2019 to February 2020 and used 2% CHG wet wipes for bathing every other day. The study outcome was to compare the effects on HAIs, catheter-associated urinary tract infections (CAUTIs), central line-associated bloodstream infections (CLABSIs), and ventilator-associated pneumonia (VAP) between these two groups. Results: A total of 731 patients in the MICU participated in the study over 12 months. HAIs were significantly different between the experimental (5.9‰) and control (8.9‰) groups, and CAUTIs were also considerably different between the experimental (1.1‰) and control (5.2‰) groups. In contrast, CLABSIs and VAP did not show differences between these two groups. Conclusions: Bathing with 2% CHG every 2 days for 12 months was associated with reduced HAIs and CAUTIs in the MICU. However, strict aseptic procedures still should be followed during routine care.

Indexed as

Bathing every other dayChlorhexidine gluconateHealthcare-associated infectionsMedical intensive care unit

Identifiers

PMID41883626
PMCPMC13010095

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.