Evidence map›Paper›PMID 41883391›Full record

ArticleOpen life sciences2025

Impact of semaphorin, Sema3F, on the gene transcription and protein expression of CREB and its binding protein CREBBP in primary hippocampal neurons of rats.

Ting Lv, Xiao-Yang Liu, Jun-Xian Fu, Zhi-Dong Qiao, Guang-Lu Yang

Abstract read
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ting LvDepartment of Pediatrics, Erdos Central Hospital, Ordos, 017010, China.
Xiao-Yang LiuDepartment of Pediatrics, Inner Mongolia Autonomous Region Maternal and Child Health Care Hospital, Hohhot, 010010, China.
Jun-Xian FuDepartment of Pediatrics, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, China.
Zhi-Dong QiaoDepartment of Pediatrics, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, China.
Guang-Lu YangDepartment of Pediatrics, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The temporal effects of Semaphorin 3F (Sema3F), a secreted signaling protein, on the transcription and protein expression of cAMP response element-binding protein (CREB) and CREB-binding protein (CREBBP) were evaluated in primary hippocampal neurons derived from Sprague-Dawley rats, with the aim of elucidating their potential involvement in axonal development. An

Indexed as

CREBCREBBPprimary hippocampal neuronal system of ratsSD ratSema3F

Identifiers

PMID41883391
PMCPMC13011598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.