Evidence map›Paper›PMID 41883381›Full record

ArticleEnvironment & health (Washington, D.C.)2026

Molecular Landscape Remodeling Unravels the Cross-Links of Microplastics-Induced Lipidomic Fluctuations, Nutrient Disorders and Energy Disarrangements.

Miao Wang, Jing Wang, Xinglin Sun, Kena Zhang, Jing Gao, Xiaoying Xu, Jiarui Wu, Fangfang Tao, Dayi Zhang, Mingying Liu

Abstract read
In one paragraph

Article in Environment & health (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Miao WangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jing WangThe Third School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Xinglin SunSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Kena ZhangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jing GaoKey Laboratory of Groundwater Resources and Environment, Ministry of Education, Changchun 130021, China.ORCID https://orcid.org/0009-0009-4911-2015
Xiaoying XuSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jiarui WuThe Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Fangfang TaoSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Dayi ZhangThe Third School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0002-4175-5982
Mingying LiuSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0001-6261-8832

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microplastics are emerging contaminants that pose health risks. They can cause hepatic lipid interventions, but the underlying mechanisms require investigation. This study assessed the retention of polypropylene microplastics in mouse liver and determined the intercorrelations between hepatic lipid fluctuations and transcriptomic changes. Microplastic-induced liver dysfunction was confirmed by the variations of transamination, cholesterol metabolism, biotransformation, and redox state. Chronic high-dose treatment induced distinct pathological changes, including regional fibrotic remodeling and ultrastructural mitochondrial abnormalities. Raman biospectra of liver slice proposed vital peaks of 1060, 1132, 1168, 1340, 1446, 1618, and 1670 cm

Indexed as

health riskslipid metabolism disorderPolypropylene microplasticsRaman spectratranscriptomic data

Identifiers

PMID41883381
PMCPMC13010300

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.