ArticleJournal of the National Cancer Institute2026
Declines in cervical cancer incidence among young women in the United States.
Article in Journal of the National Cancer Institute, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We calculated age-standardized cervical cancer incidence rates and trends by histologic type among women aged 15-29 years, using cancer registry data covering approximately 99% of the US population. We examined differences in incidence rates from the earliest to the most recent study period and quantified changes over time using joinpoint regression. Incidence rates for cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC) decreased significantly during 1999-2022 in all age groups (15-20, 21-24, 25-29 years). Among women aged 15-20 years, cervical SCC rates were stable from 1999 to 2010 but declined substantially by 24.2% (95% confidence interval = -44.4 to -18.0) each year from 2010 to 2022, with only a few cases reported during 2017-2022. These findings show that cervical cancer incidence has declined among adolescents and young adult women in the United States, particularly in more recent years, highlighting the population-level impact of cervical cancer prevention measures.
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