Evidence map›Paper›PMID 41882908›Full record

ArticleThe Journal of veterinary medical science2026

Malignant epithelial tumors associated with Felis catus papilloma virus type 3 and type 4 infections at distinct anatomical sites in a domestic cat.

Hinata Abe, Nanami X Kato, Mika Tanabe, Taichi Shimabukuro, Saki Hashimoto, Takuya Hirai, Naoyuki Fuke, Akatsuki Saito

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hinata AbeLaboratory of Veterinary Pathology, Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan.
Nanami X KatoLaboratory of Veterinary Microbiology, Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan.
Mika TanabeVeterinary Pathology Diagnostic Center, Fukuoka, Japan.
Taichi ShimabukuroRyukyu Animal Medical Center, Okinawa, Japan.
Saki HashimotoSaki Animal Hospital, Fukuoka, Japan.
Takuya HiraiLaboratory of Veterinary Pathology, Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan.
Naoyuki FukeLaboratory of Veterinary Pathology, Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan.
Akatsuki SaitoLaboratory of Veterinary Microbiology, Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 12-year-8-month-old neutered male cat presented with multiple nail bed masses and an ulcerative lip lesion. PCR identified Felis catus papillomavirus type 3 (FcaPV3) in the nail masses and type 4 (FcaPV4) in the lip lesion. Histopathology revealed basosquamous cell carcinoma (BSCC) in the digits and Bowenoid in situ carcinoma (BISC) in the lip. Immunohistochemistry showed that tumor cells in both BSCC and BISC were positive for p16 and p63 and weakly positive for pRb; p53 was negative in BSCC but weakly positive in BISC. In situ hybridization confirmed FcaPV3 and FcaPV4 E6 genes in digital and lip tumors, respectively. Over 6 months, viral sequencing showed 23 nucleotide changes in FcaPV3, suggesting viral evolution. This is the first report of distinct malignant epithelial tumors independently induced by FcaPV3 and FcaPV4 in a cat.

Indexed as

Cat DiseasesPapillomaviridaePapillomavirus InfectionsSkin NeoplasmsAnimalsCatsMaleBasosquamous cell carcinomaBowenoid in situ carcinomaconcurrent infectionFelis catus papillomavirus

Identifiers

PMID41882908
PMCPMC13183512

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.