Evidence map›Paper›PMID 41882802›Full record

Observational studyWorld journal of surgery2026

Determinants of Compliance to Enhanced Recovery Protocol After Emergency Laparotomy.

Marco Ceresoli, Chiara Fumagalli, Alan Biloslavo, Antonio La Greca, Michele Carlucci, Giovanni Pesenti, Savino Occhionorelli, Pietro Bisagni, Carlo Feo, Dario Tartaglia and 9 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in World journal of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Marco CeresoliUniversity of Milano-Bicocca, School of Medicine and Surgery, Monza, Italy.
Chiara FumagalliUniversity of Milano-Bicocca, School of Medicine and Surgery, Monza, Italy.
Alan BiloslavoDepartment of General Surgery, Cattinara University Hospital, ASUGI, Trieste, Italy.ORCID https://orcid.org/0000-0003-0883-2744
Antonio La GrecaDip.to Scienze Mediche e Chirurgiche, UOC Chirurgia d'Urgenza e Trauma, Fondazione Policlinico Universitario A. Gemelli IRCCS Roma - Università Cattolica del Sacro Cuore, Milano, Italy.
Michele CarlucciDepartment of Emergency and General Surgery, IRCCS San Raffaele Hospital, Milano, Italy.
Giovanni PesentiUOC Chirurgia Generale e d'Urgenza, Dip. chirurgico, H. A. Manzoni, Lecco, Italy.
Savino Occhionorellis.s.d. Emergency surgery, Surgical Department, University of Ferrara, Ferrara, Italy.
Pietro BisagniDepartment of Surgery, ASST Lodi, Lodi, Italy.
Carlo FeoUOC Chirurgia Generale Provinciale, Azienda USL di Ferrara - Università di Ferrara, Ferrara, Italy.
Dario TartagliaGeneral, Emergency Surgery Unit and Trauma Center, Pisa University Hospital, Pisa, Italy.ORCID https://orcid.org/0000-0003-1615-3370
Dario PariniGeneral Surgery Department, Santa Maria della Misericordia Hospital, Rovigo - ULSS 5, Rovigo, Italy.
Matteo RunfolaGeneral and Emergency Surgery Unit, Department of Emergency, ARNAS "G. Brotzu", Cagliari, Italy.
Riccardo SomigliDipartimento Chirurgia usl toscana centro- ospedale Santa Maria Nuova, Firenze, Italy.
Diego ViscontiChirurgia Generale d'Urgenza e PS, AOU Città della Salute e della Scienza, Torino, Italy.
Diego MarianiGeneral Surgery, Ospedale di Legnano, ASST ovest Milanese, Legnano, Italy.
Diletta CassiniGeneral Surgery, ASST Milano-Nord, Sesto San Giovanni, Italy.
Andrea MingoliPresident of the Italian Society of Emergency Surgery and Trauma (SICUT), Roma, Italy.
Marco BragaUniversity of Milano-Bicocca, School of Medicine and Surgery, Monza, Italy.
Study Collaborative Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnhanced recovery protocols (ERP) are comprehensive, evidence-based approaches aimed at accelerating patient recovery and improving surgical results; increasing evidence exists about their adoption in emergency laparotomy. The study aimed to evaluate the compliance to the proposed postoperative pathway and the determinants of late recovery.

methodsThis is a multicenter observational prospective study involving 13 Italian centers. Inclusion criteria targeted adults undergoing emergency surgery for intestinal occlusion or perforation. The primary end point was the early recovery rate (discontinuation of intravenous fluids and the initiation of oral intake on postoperative day three) and its determinants. The secondary end point were reasons for uncompliance to postoperative ERP items.

resultsBetween March 2023 and March 2024, 760 patients were recruited and analyzed, 60.2 with intestinal obstruction and 39.8 with intra-abdominal infections. Recovery was achieved by 53.7% of patients on postoperative Day 3. Among determinants, clinical frailty and ASA status negatively correlated with recovery whereas the absence of surgical drains, anesthetic depth monitoring and intraoperative goal-directed fluid therapy positively correlated with recovery. An analysis of the reasons for noncompliance with postoperative items revealed that aside from postoperative complications, the most frequently cited reason was protocol deviation for clinical decision, accounting for approximately 10%-15% of noncompliance for each item.

conclusionsThis study showed that half of the patients reached the recovery goal on postoperative Day 3 and that early recovery after surgery is influenced both by intrinsic patient factors and by adherence to ERP strategies. Future research should prioritize strategies to improve ERP adherence and postoperative compliance.

Indexed as

Enhanced Recovery After SurgeryGuideline AdherenceIntestinal ObstructionIntestinal PerforationLaparotomyAgedEmergenciesFemaleHumansItalyMaleMiddle AgedProspective Studiesemergency general surgeryenhanced recovery protocolERASperioperative care

Identifiers

PMID41882802
PMCPMC13206338

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.