ArticleJournal of medical case reports2026
Coinfection meningitis caused by Lysinibacillus sphaericus and Brevundimonas diminuta in a pediatric patient with cerebral atrophy: a case report.
Article in Journal of medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Polymicrobial Catheter-Related Bloodstream Infection InvolvingMicroorganisms · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntracranial infections caused by rare environmental pathogens pose diagnostic and therapeutic challenges. This report presents the first documented case of meningitis caused by coinfection with Lysinibacillus sphaericus and Brevundimonas diminuta. CASE PRESENTATION: A 10-year-old Han Chinese, nonverbal male with cerebral atrophy developed fever and vomiting following Ommaya pump implantation. Cerebrospinal fluid (CSF) culture and preliminary matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) suggested coinfection with L. sphaericus and B. diminuta, which was subsequently confirmed by 16S rRNA gene sequencing. Initial vancomycin monotherapy failed, but treatment was successfully switched to intravenous meropenem combined with intrathecal gentamicin via the Ommaya pump.
conclusionsThis case highlights that even immunocompetent hosts with indwelling neurological devices are susceptible to opportunistic infections by environmental pathogens. Molecular diagnostic techniques are crucial for confirming rare pathogens, and intrathecal administration can serve as a vital adjunctive strategy when systemic therapy is ineffective.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.