Evidence map›Paper›PMID 41882496›Full record

ArticleJournal of proteome research2026

What Does Next-Generation Mass Spectrometry Offer for Proteomics? A Comprehensive Platform Comparison.

Filipa Blasco Tavares Pereira Lopes, Daniela Schlatzer, Tara Sudhadevi, Anantha Harijith, Marzieh Ayati, Mehmet Koyutürk, Mark R Chance

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of proteome research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Filipa Blasco Tavares Pereira LopesCenter for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio 44106, United States.ORCID 0000-0002-2859-1506
Daniela SchlatzerCenter for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Tara SudhadeviDepartment of Pediatrics, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Anantha HarijithDepartment of Pediatrics, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Marzieh AyatiDepartment of Computer Science, University of Texas Rio Grande Valley, Edinburg 78539, United States.ORCID 0000-0002-5280-5738
Mehmet KoyutürkCenter for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Mark R ChanceCenter for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio 44106, United States.ORCID 0000-0002-2991-6405

Funding

Q Exactive HF-X hybrid quadrupole-Orbitrap mass spectrometer (QE HF-X)S10OD028614 · OD · CASE WESTERN RESERVE UNIVERSITY · PI CHANCE, MARK R · 2020 to 2020
$600k
NIH HHS S10 OD028614
6 · The paper itself

Abstract

Next-generation mass spectrometry platforms (Orbitrap Astral, timsTOF Ultra) are reshaping proteomics by enhancing analytical depth and sensitivity. We compared these platforms against Orbitrap Exploris 480 using neonatal mouse lung tissues from a bronchopulmonary dysplasia model (

Indexed as

Bronchopulmonary DysplasiaMass SpectrometryProteomeProteomicsAnimalsLungMiceProteomebronchopulmonary dysplasiadata-dependent acquisitiondata-independent acquisitionDDADIAOrbitrap AstralproteomicstimsTOF Ultra

Identifiers

PMID41882496
PMCPMC13054874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.