ArticleDiscover oncology2026
First reported case in Brazil of intraventricular pilocytic astrocytoma in an adult patient with literature review.
Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPilocytic astrocytomas (PAs) are central nervous system tumors that predominantly occur during the first two decades of life and typically arise in the cerebellum, optic pathways, hypothalamus, or brainstem. Intraventricular PAs are extremely uncommon, accounting for less than 4% of all cases, and adult presentations are particularly rare. We report the first documented case of an intraventricular PA in an adult patient in Brazil and highlight its clinical and therapeutic relevance. CASE REPORT: A 32-year-old Brazilian woman presented with a secondary epileptic seizure. Magnetic resonance imaging revealed an expansive lesion in the left lateral ventricle. The tumor was surgically resected, and histopathological examination showed a biphasic neoplasm with eosinophilic granular bodies and microcystic areas. Immunohistochemical analysis demonstrated positivity for glial fibrillary acidic protein (GFAP) and oligodendrocyte transcription factor 2 (OLIG2), with no expression of mutant isocitrate dehydrogenase 1 protein (IDH1 R132H). Expression of 5'-methylthioadenosine phosphorylase (MTAP), alpha-thalassemia/mental retardation syndrome X-linked (ATRX), and the tumor suppressor protein p16 (INK4a) was retained. The Ki-67 (MIB-1) proliferation index was low, at approximately 1%, consistent with a WHO Grade 1 glioma.
conclusionsThis case illustrates a rare intraventricular PA in an adult, confirmed through clinical, radiological, and histopathological integration. It emphasizes the importance of including PA in the differential diagnosis of intraventricular tumors in adults and may contribute to guiding recognition and management of rare ventricular tumors in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.