ArticleClinical oral investigations2026
Exploring the relationship between insulin resistance, wrist circumference, dental age, and skeletal maturation in growing patients with overweight and obesity: a pilot study.
Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThe global prevalence of childhood obesity has surged in recent years. Children who are overweight or obese frequently exhibit accelerated dental development, skeletal maturation, and earlier onset of puberty. This study explores the relationship between insulin resistance and the advancement of dental and skeletal maturation in growing individuals. Additionally, it evaluates wrist circumference—an easily measurable clinical marker associated with insulin resistance—as a potential independent predictor of dental advancement in orthodontic patients. MATERIALS AND
methodsAssessed parameters included chronological age (7–14 years), anthropometric measurements (weight, height, body mass index [BMI], waist and wrist circumference, waist-to-height ratio [WHtR]), glucose profile, insulin resistance markers, cervical vertebrae maturation stage (CVMS), and dental age advancement (calculated as dental age minus chronological age). Eighteen patients were stratified into three BMI-based groups: normal-weight subjects, patients who are overweight, and patients who are obese.
resultsStatistical analysis showed a strong association between BMI and dental age advancement. Wrist circumference and WHtR were stronger and more reliable predictors of skeletal maturation than BMI. Insulin resistance was significantly correlated with dental age advancement, emphasizing the influence of metabolic health on dental development. Multivariate analysis identified wrist circumference and WHtR as key predictors of dental age advancement.
conclusionsThis pilot study suggests a potential association between BMI, insulin resistance, anthropometric measures, and the advancement of dental and skeletal maturation in children who are overweight or obese. These preliminary findings highlight the possible influence of metabolic health on growth patterns. CLINICAL RELEVANCE: Considering metabolic indicators such as wrist circumference and waist-to-height ratio in growing patients may help orthodontists identify those at risk of accelerated dental development and optimize the timing of individualized treatment.
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