Evidence map›Paper›PMID 41882336›Full record

ReviewNature reviews. Cardiology2026

Drug-coated balloon angioplasty for coronary and peripheral artery disease: latest evidence and clinical indications.

Rory Durand, Daniel O'Callaghan, J J Coughlan, Salvatore Cassese, Robert A Byrne

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rory DurandCardiovascular Research Institute Dublin, Mater Private Network, Dublin, Ireland.ORCID http://orcid.org/0000-0003-2712-2131
Daniel O'CallaghanCardiovascular Research Institute Dublin, Mater Private Network, Dublin, Ireland.ORCID http://orcid.org/0000-0002-4480-9990
J J CoughlanCardiovascular Research Institute Dublin, Mater Private Network, Dublin, Ireland.ORCID http://orcid.org/0000-0001-6086-3279
Salvatore CasseseKlinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Munich, Germany.ORCID http://orcid.org/0000-0002-8668-4313
Robert A ByrneCardiovascular Research Institute Dublin, Mater Private Network, Dublin, Ireland. robertabyrne@rcsi.ie.ORCID http://orcid.org/0000-0001-5224-6393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-coated balloons (DCBs) are devices used for the treatment of both coronary artery disease (CAD) and peripheral artery disease (PAD). One of the hypothesized advantages of DCB angioplasty over stent implantation is that DCB angioplasty does not result in the presence of a permanent metallic scaffold in the vessel wall. However, DCB angioplasty also has some important limitations, such as a potentially lower efficacy compared with other modalities; therefore, the role of DCBs in the treatment of CAD and PAD is not fully defined. Over the past 20 years, many clinical trials have been performed to investigate the use of these devices for a variety of indications. In this Review, we describe the device design and mechanism of action of DCBs and discuss important procedural considerations for successful DCB use. We summarize the scientific and clinical evidence for DCB angioplasty in CAD and PAD. In addition, we highlight the recommendations for DCB use in clinical practice guidelines and provide perspectives on the potential future role that DCB angioplasty might have in the treatment of CAD and PAD.

Indexed as

Angioplasty, BalloonAngioplasty, Balloon, CoronaryCardiovascular AgentsCoated Materials, BiocompatibleCoronary Artery DiseasePeripheral Arterial DiseaseEquipment DesignHumansTreatment OutcomeCardiovascular AgentsCoated Materials, Biocompatible

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.