Evidence map›Paper›PMID 41882309›Full record

ArticleNano-micro letters2026

Phage-Inspired Artificial Peroxidases with Robust Sub-Nanometer Cluster Sites for Efficient Oral Biofilm Elimination and Dental Caries Prevention.

Huang Zhu, Ting Wang, Shihuan Gao, Wei Geng, Tian Ma, Liang Cheng, Xianglong Han, Jiuhong Deng, Shanshan Gao, Chong Cheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano-micro letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Huang ZhuState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, People's Republic of China.
Ting WangCollege of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, 610065, People's Republic of China.
Shihuan GaoCollege of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, 610065, People's Republic of China.
Wei GengCollege of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, 610065, People's Republic of China.
Tian MaCollege of Polymer Science and Engineering, State Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, 610065, People's Republic of China.
Liang ChengDepartment of Materials Science and Engineering, The Macau University of Science and Technology, Taipa, 999078, Macau, People's Republic of China.
Xianglong HanState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, People's Republic of China.
Jiuhong DengState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, People's Republic of China. jiuhongdeng@163.com.
Shanshan GaoState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, People's Republic of China. christina12357@163.com.
Chong ChengState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, People's Republic of China. chong.cheng@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental caries, a highly prevalent oral disease, is primarily driven by pathogenic biofilms; however, current antimicrobials exhibit limited efficacy and poor specificity against cariogenic biofilms. Although nanobiocatalysts that can produce reactive oxygen species represent a promising alternative to conventional antimicrobials, most current designs fail to achieve robust bacterial interaction and exhibit insufficient disruption of biofilm integrity. To address these challenges, we report the de novo design of phage-inspired artificial peroxidases (IrNC@TiO

Indexed as

Artificial peroxidasesBiofilm eradicationBioinspired designDental cariesROS generation

Identifiers

PMID41882309
PMCPMC13018512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.