Evidence map›Paper›PMID 41882254›Full record

ArticleScientific reports2026

A cross sectional study of the autonomic function at different recovery phases in SARS-CoV-2 patients without orthostatic symptoms.

Maria Teresa La Rovere, Roberto Maestri, Elena Robbi, Angelo Caporotondi, Marta Lovagnini, Nicolino Ambrosino

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Teresa La RovereCardiology Department, Istituti Clinici Scientifici Maugeri IRCCS, Montescano, Pavia, Italy. mariateresa.larovere@icsmaugeri.it.
Roberto MaestriBiomedical Engineering Department, Istituti Clinici Scientifici Maugeri IRCCS, Montescano, Pavia, Italy.
Elena RobbiCardiology Department, Istituti Clinici Scientifici Maugeri IRCCS, Montescano, Pavia, Italy.
Angelo CaporotondiCardiology Department, Istituti Clinici Scientifici Maugeri IRCCS, Montescano, Pavia, Italy.
Marta LovagniniCardiology Department, Istituti Clinici Scientifici Maugeri IRCCS, Montescano, Pavia, Italy.
Nicolino AmbrosinoRespiratory Department, Istituti Clinici Scientifici Maugeri IRCCS, Montescano, Pavia, Italy.

Funding

Italian Ministry of Health, Ricerca Corrente Reti-Rete Cardiologica RCR-2020-23670065 and RCR-2021-23671212
6 · The paper itself

Abstract

Autonomic nervous system involvement in COVID-19 survivors has been reported. This study aimed to assess heart rate variability (HRV) and baroreflex sensitivity (BRS) in COVID-19 survivors without orthostatic symptoms at different times after infection. Participants were classified as post-acute (PA, < 120 days) or long-term (LT, ≥ 120 days) according to time since positive swab. Mean heart rate (HR), time- (SDNN, RMSSD, pNN50) and frequency-domain (LF power, HF power, LF/HF) were computed. BRS was assessed by the sequence (BRS_seq) and the transfer function (BRS_TF) methods. We studied 37 PA and 36 LT patients and 50 age- and sex-matched healthy controls (HC). Compared to HC, PA patients exhibited significantly lower values for SDNN, RMSSD, pNN50, log-transformed LF and HF power, BRS_TF and BRS_seq, and higher HR and LF/HF ratio. Similar trends were observed in LT patients, with the exception of HR and LF/HF, where differences were not significant. Significant differences between PA and LT were found in HR (77.2 ± 10.7 vs. 69.8 ± 10.7 bpm, p = 0.002), log-transformed HF power (3.1 ± 1.2 vs. 3.8 ± 1.2 log-ms

Indexed as

Autonomic Nervous SystemCOVID-19AdultAgedBaroreflexCase-Control StudiesCross-Sectional StudiesFemaleHeart RateHumansMaleMiddle AgedPost-Acute COVID-19 SyndromeSARS-CoV-2Autonomic nervous systemBaroreflex sensitivityCOVID-19Heart rate variabilityPost-acute sequelae of COVID-19

Identifiers

PMID41882254
PMCPMC13168453

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.