Evidence map›Paper›PMID 41882002›Full record

ArticleNature communications2026

Therapeutic potential of dihydronicotinamide riboside (NRH) on obesity and glucose intolerance in mice.

Marie Rumpler, Guido van Mierlo, Kasper T Vinten, Maria Pilar Giner, Stefan Christen, Faisal Hayat, Mikhail V Makarov, Vincent Gardeux, Julie Russeil, Bauke V Schomakers and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Marie RumplerLaboratory of Systems Biology and Genetics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Guido van MierloLaboratory of Systems Biology and Genetics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Kasper T VintenLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9661-4709
Maria Pilar GinerNestlé Institute of Food Safety and Analytical Sciences, Nestlé Research, Lausanne, Switzerland.ORCID http://orcid.org/0009-0004-3206-7119
Stefan ChristenNestlé Institute of Food Safety and Analytical Sciences, Nestlé Research, Lausanne, Switzerland.
Faisal HayatMitchell Cancer Institute, F.P. Whiddon College of Medicine, University of South Alabama, 1660 Springhill Avenue, Mobile, AL, USA.
Mikhail V MakarovMitchell Cancer Institute, F.P. Whiddon College of Medicine, University of South Alabama, 1660 Springhill Avenue, Mobile, AL, USA.ORCID http://orcid.org/0000-0002-0932-6715
Vincent GardeuxLaboratory of Systems Biology and Genetics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-8954-2161
Julie RusseilLaboratory of Systems Biology and Genetics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-0880-9483
Bauke V SchomakersLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Laurine van GijnLaboratory of Systems Biology and Genetics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Horia HashimiLaboratory of Systems Biology and Genetics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-1864-7449
Clémence SteinerLaboratory of Systems Biology and Genetics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Judith Giroud-GerbetantNestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.
Magali JoffraudNestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.ORCID http://orcid.org/0009-0003-1848-9588
Jose Luis Sanchez GarciaNestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.
Sofia MocoNestlé Institute of Food Safety and Analytical Sciences, Nestlé Research, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-8170-8876
Marie E MigaudMitchell Cancer Institute, F.P. Whiddon College of Medicine, University of South Alabama, 1660 Springhill Avenue, Mobile, AL, USA.ORCID http://orcid.org/0000-0002-9626-2405
Riekelt H HoutkooperLaboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9961-0842
Bart DeplanckeLaboratory of Systems Biology and Genetics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-9935-843X
Carles CantoLaboratory of Systems Biology and Genetics, Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. carles.canto@epfl.ch.ORCID http://orcid.org/0000-0002-5167-7922

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) MSCA-DN-NADIS no. 101073251U.S. Department of Health & Human Services | NIH | National Center for Complementary and Integrative Health (NCCIH) R21 AAT009908-01
6 · The paper itself

Abstract

NAD

Indexed as

Glucose IntoleranceNiacinamideObesityRibonucleosidesAnimalsDietary SupplementsDiet, High-FatLipid MetabolismLiverMaleMiceMice, Inbred C57BLNADNADNiacinamideRibonucleosides

Identifiers

PMID41882002
PMCPMC13181051

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.