ArticleBDJ open2026
In vitro study on the neutralization potential of particulate hydroxyapatite in erosive acids.
Article in BDJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Tooth Enamel Demineralization: Caries and Erosion from the Viewpoint of Chemistry.Dentistry journal · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveHydroxyapatite (HAP; Ca MATERIALS AND
methods5.0% (w/v) particulate HAP was added to hydrochloric acid, phosphoric acid, citric acid, and lactic acid (37 °C, 0.1 M), as well as to Sprite® and Coca-Cola®, all under continuous stirring. pH values were measured after equilibration. Neutralization kinetics of HAP were investigated in Sprite® and Coca-Cola® within the first 30 s after addition of 0.15% (w/v), 0.5% (w/v), and 5.0% (w/v) HAP. Scanning electron microscopy (SEM) and X-ray powder diffraction (XRD) were employed to investigate crystallite morphology and composition. Atomic absorption spectroscopy (AAS) was conducted to analyze Ca
resultsThe investigated HAP shows a significant increase in pH in all systems and neutralizes between 98.0% and 99.9% of the acidic protons in the equilibrium. Up to 2619 mg L
conclusionsThe study shows that HAP used in oral care formulations can efficiently counteract acids by increasing pH value and releasing Ca
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Registered trials
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