ArticleJournal of fish diseases2026
First Report of Nocardiosis Caused by Nocardia seriolae in Farmed Spotted Scat (Scatophagus argus).
Article in Journal of fish diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Nocardiosis is a chronic bacterial disease causing significant losses in marine aquaculture worldwide. This study reports the first confirmed outbreak of nocardiosis caused by Nocardia seriolae in farmed spotted scat (Scatophagus argus) in Vietnam, with cumulative mortalities reaching up to 70%. Diseased fish exhibited skin ulceration and disseminated white nodules in internal organs and musculature. Histopathological examination revealed typical granulomatous lesions containing abundant Gram-positive, branching filamentous bacteria. A bacterium with consistent morphological characteristics was isolated from affected organs, and molecular identification based on 16S rRNA gene sequencing and species-specific PCR confirmed the pathogen as N. seriolae. The experimental challenge reproduced the clinical signs and pathological features of natural infection, with an estimated LD50 of 5.3 × 10
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