Evidence map›Paper›PMID 41881768›Full record

ReviewTrends in genetics : TIG2026

Machine learning for evolutionary genetics and molecular evolution.

Nicolas Svetec, UnJin Lee, Li Zhao

Abstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicolas SvetecLaboratory of Evolutionary Genetics and Genomics, The Rockefeller University, New York, NY 10065, USA.
UnJin LeeLaboratory of Evolutionary Genetics and Genomics, The Rockefeller University, New York, NY 10065, USA.
Li ZhaoLaboratory of Evolutionary Genetics and Genomics, The Rockefeller University, New York, NY 10065, USA. Electronic address: lzhao@rockefeller.edu.

Funding

The genetic and epigenetic mechanisms of phenotypic innovationhttps://apps.era.nih.gov/gm/reportCheckList.do?applicationID=9798249R35GM133780 · NIGMS · ROCKEFELLER UNIVERSITY · PI Li Zhao · 2019 to 2026
$3.5M
NIGMS NIH HHS R35 GM133780
6 · The paper itself

Abstract

Over the past decade, the rapid expansion of large-scale data and advances in computational power have allowed machine learning (ML), especially deep learning, to reshape many areas of biological research. Evolutionary genetics and molecular evolution are also poised for a similar transformation. In this review, we discuss key advances and ongoing challenges in applying ML to the study of genetics and evolution, and we highlight the potential of artificial intelligence to connect genotype, phenotype, and evolutionary history.

Indexed as

Evolution, MolecularMachine LearningAnimalsArtificial IntelligenceGenetics, PopulationGenotypeHumansPhenotypeSoft Computingartificial intelligencedeep learningmachine learningmolecular evolutionpopulation genetics

Identifiers

PMID41881768
PMCPMC13025824

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.