ArticleJournal of vascular surgery. Venous and lymphatic disorders2026
Endovascular treatment of acute upper extremity deep vein thrombosis in Paget-Schroetter syndrome: A longitudinal analysis of three endovascular techniques.
Article in Journal of vascular surgery. Venous and lymphatic disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Balancing early thrombus removal with durable decompression in Paget-Schroetter syndrome.Journal of vascular surgery. Venous and lymphatic disorders · 2026Article
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7 authors.
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Abstract
objectiveOptimal procedural strategies for the management of acute upper extremity deep vein thrombosis (UEDVT) due to Paget-Schroetter syndrome are poorly studied due to its rarity. The aim of this study was to compare short-term patency, complication rates, and course after endovascular therapy of acute UEDVT due to Paget-Schroetter syndrome.
methodsIn this single-center retrospective longitudinal study, data of consecutive patients with acute Paget-Schroetter syndrome treated with interventional thrombectomy at the University Hospital Zurich with any available device: computer assisted vacuum thrombectomy (CAVT), AngioJet/Zelante catheter, or catheter-directed thrombolysis (CDT) was collected. We studied the need for reintervention, primary and secondary patency, and course of symptoms at 2 weeks, 3 months, and 6 months.
resultsWe included 41 patients with acute UEDVT treated between 2017 and 2025. The median age was 34 years; 61% were men, and 41% were athletes. After a median symptom duration of 4 days, they received thrombectomy with AngioJet/Zelante (61%), CAVT (17%), and CDT (22%). Sixteen patients (39%) required reintervention, mostly within 48 hours (62.5%). Primary patency was 60% (24/40) at 2 weeks, 52.6% (20/38) at 3 months, and 54.1% (20/37) at 6 months (P = .08 for between-group difference). Secondary patency was 72%, 76%, and 86%, respectively. Kaplan-Meier analysis showed higher freedom from reintervention after CAVT (P = .04). Symptom relief occurred mainly within the first 2 weeks: swelling (98% to 17%), pain (60% to 14%). Cyanosis resolved by 6 months, whereas paresthesia slightly increased (15% to 23%). Only one major and one minor bleeding event occurred.
conclusionsCatheter-directed therapies appeared to be safe and effective for UEDVT due to Paget-Schroetter syndrome. In this exploratory study, bearing the small sample size, the data suggest that single-session thrombectomy (especially CAVT) may be associated with fewer reinterventions and higher primary patency.
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