ArticleSurgery2026
Repeated lengthening using distraction enterogenesis: A porcine model.
Article in Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Alterations in biopterin metabolism and the effects of tetrahydrobiopterin supplementation in a rat model of short bowel syndrome.Pediatric surgery international · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionSpring-mediated distraction enterogenesis aims to use mechanical stretch to generate new functional intestinal tissue in patients with short bowel syndrome. Because of the incremental nature of spring-mediated distraction enterogenesis, patients may require multiple spring insertions to produce enough tissue to wean off parenteral nutrition. We aim to demonstrate the feasibility of repeated lengthening within the same intestinal segment.
methodsJuvenile Yucatan pigs underwent a laparotomy to introduce a gelatin-encapsulated nitinol spring into the jejunum. After 14-21 days, a second laparotomy was performed to remove the initial spring and insert a new compressed spring with a greater force constant into a portion of the previously lengthened jejunum. After 7 days, the pigs were killed, and samples were collected.
resultsSpring insertion produced a significant increase in jejunal length when compared to controls. Both the initial and the subsequent stronger springs produced an equivalent amount of lengthening. Crypt depth, mucosal thickness, muscularis thickness, and the outer serosal perimeter of the repeatedly lengthened jejunal segments all increased compared with control segments.
conclusionPreviously lengthened segments of jejunum were successfully relengthened using spring-mediated distraction enterogenesis in a porcine model. This suggests that patients with short bowel syndrome may be offered repeat distraction procedures to achieve a greater increase in bowel length than a single spring-mediated distraction enterogenesis procedure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.