Evidence map›Paper›PMID 41880656›Full record

ArticlePlant biology (Stuttgart, Germany)2026

PgUGT84K2, a Panax ginseng glycosyltransferase, catalyses IBA glycosylation and enhances abiotic stress tolerance in transgenic Arabidopsis.

F Chang, S Ma, Y Yu, Z Wang, J He, X Gong, G Zhang

Abstract read
In one paragraph

Article in Plant biology (Stuttgart, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

F ChangSchool of medicine, Linyi University, Linyi, People's Republic of China.
S MaSchool of medicine, Linyi University, Linyi, People's Republic of China.
Y YuSchool of medicine, Linyi University, Linyi, People's Republic of China.
Z WangSchool of medicine, Linyi University, Linyi, People's Republic of China.
J HeKey Laboratory of Southwest China Wildlife Resources Conservation, Ministry of Education, China West Normal University, Nanchong, People's Republic of China.
X GongSchool of medicine, Linyi University, Linyi, People's Republic of China.
G ZhangSchool of medicine, Linyi University, Linyi, People's Republic of China.ORCID https://orcid.org/0009-0004-6700-8514

Funding

National Natural Science Foundation of China Grants 31700238Shandong Provincial Natural Science Foundation of China ZR2017PC007
6 · The paper itself

Abstract

Glycosylation plays a crucial role in modulating auxin homeostasis through the formation of auxin glycoside conjugates. However, the involved mechanisms and relevant physiological significances are largely unknown or poorly understood. PgUGT84K2 enzyme was purified and the enzyme activity was identified by HPLC and LC/MS analyses. We heterologously overexpressed PgUGT84K2 in Arabidopsis thaliana and analysed glycosyltransferase activity and glycosylated metabolites IBA-Glc in transgenic plants. Drought and salt stress assays of the transgenic plants were conducted and the expression of related genes was analysed by quantitative RT-PCR. Panax ginseng glycosyltransferase PgUGT84K2 was at the first time identified to be an IBA glycosyltransferase. Assessment of enzyme activity and IBA conjugates in transgenic plants ectopically expressing PgUGT84K2 indicated that the PgUGT84K2 catalytic specificity was maintained in planta. Heterologous overexpression of PgUGT84K2 in Arabidopsis thaliana led to significantly enhanced tolerance to drought and salt stresses, with improved germination rates, seedling greening rates and seedling survival rates than the wild type. Overexpression of PgUGT84K2 enhanced ROS scavenging in transgenic plants and quantitative RT-PCR analysis revealed the up-regulation of key antioxidant enzyme genes SOD1, SOD3, CAT2, CAT3 and ABA biosynthesis genes AAO1, AAO3, along with down-regulation of ABA signalling repressors EM1 and EM6. Our results suggest that PgUGT84K2, an IBA glycosyltransferase, might enhance stress tolerance through modulating ABA signalling and enhancing ROS scavenging via the enzymatic antioxidant system, and provide a potential strategy to breed drought and salt resistant P. ginseng.

Indexed as

ArabidopsisGlycosyltransferasesPanaxPlant ProteinsDrought ResistanceDroughtsGene Expression Regulation, PlantGlycosylationPlants, Genetically ModifiedReactive Oxygen SpeciesSeedlingsStress, PhysiologicalGlycosyltransferasesPlant ProteinsReactive Oxygen SpeciesArabidopsisauxinsglycosyltransferasePanax ginsengPgUGT84K2stress tolerance

Identifiers

PMID41880656
PMCPMC13358660

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.