Evidence map›Paper›PMID 41880570›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Cnpy1 is a candidate endoplasmic reticulum chaperone of vomeronasal type 2 GPCRs.

G V S Devakinandan, Abdul Rishad, Nandana Nanda, Syed Dastagir Hussain, Sishir Subedi, Adish Dani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

G V S DevakinandanTata Institute of Fundamental Research, Hyderabad 500046, India.ORCID 0009-0009-4978-7477
Abdul Rishad *Tata Institute of Fundamental Research, Hyderabad 500046, India.ORCID 0009-0006-6996-0431
Nandana Nanda *Tata Institute of Fundamental Research, Hyderabad 500046, India.ORCID 0000-0001-9193-5343
Syed Dastagir Hussain *Tata Institute of Fundamental Research, Hyderabad 500046, India.ORCID 0009-0005-2377-9322
Sishir SubediGraduate Program in Bioinformatics, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Adish DaniTata Institute of Fundamental Research, Hyderabad 500046, India.ORCID 0000-0002-5491-7709

Funding

TRANSLATION PROFILING AND NANOSCALE LOCALIZATION OF SYNAPTIC TRANSCRIPTSR21MH099798 · NIMH · WASHINGTON UNIVERSITY · PI DANI, ADISH, DOUGHERTY, JOSEPH D · 2013 to 2014
$418k
Department of Atomic Energy, Government of India (DAE) Project No RTI 4007NIMH NIH HHS R21 MH099798
6 · The paper itself

Abstract

Mouse vomeronasal sensory neurons are continuously generated from stem cells and differentiate to express either V1R or V2R G protein-coupled receptors (GPCRs), along with their respective Gαi2 or Gαo G-protein subunits. We previously reported that Gαo-type neurons exhibit elevated expression of endoplasmic reticulum (ER) chaperones and a distinctive hypertrophic, gyroid ER architecture, suggesting specialized proteostatic demands. Here, we identify a transcript for the mouse Canopy1 (

Indexed as

Endoplasmic ReticulumMolecular ChaperonesReceptors, G-Protein-CoupledVomeronasal OrganAnimalsGTP-Binding Protein alpha Subunits, Gi-GoMaleMiceMice, KnockoutSensory Receptor CellsGTP-Binding Protein alpha Subunits, Gi-GoMolecular ChaperonesReceptors, G-Protein-CoupledCnpy1endoplasmic reticulumGPCRsensory neuronsvomeronasal

Identifiers

PMID41880570
PMCPMC13037941

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.