Evidence map›Paper›PMID 41880495›Full record

ArticleScience advances2026

A conserved glycan motif induces broadly reactive functional antibodies against the zoonotic pathogen

Yao Shi, Göran Widmalm, Charlotte Sorieul, Thomas J Roodsant, Jeffrey S Rush, Natalia Korotkova, Manouk Vrieling, Antonius A C Jacobs, Mirlin Spaninks, Ries Grommen and 12 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Yao ShiDepartment of Population Health Sciences, Division Farm Animal Health, Utrecht University, Utrecht, Netherlands.ORCID 0000-0001-9628-5079
Göran WidmalmDepartment of Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden.ORCID 0000-0001-8303-4481
Charlotte SorieulLeiden Institute of Chemistry, Leiden University, Leiden, Netherlands.ORCID 0000-0003-1999-6007
Thomas J RoodsantDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC Location University of Amsterdam, Amsterdam, Netherlands.ORCID 0000-0003-0553-8734
Jeffrey S RushDepartment of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, USA.
Natalia KorotkovaDepartment of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, USA.
Manouk VrielingWageningen Bioveterinary Research, Houtribweg 39, Lelystad, Netherlands.ORCID 0000-0002-5465-4515
Antonius A C JacobsMSD Animal Health, Wim de Körverstraat 35, Boxmeer, Netherlands.
Mirlin SpaninksDepartment of Population Health Sciences, Division Farm Animal Health, Utrecht University, Utrecht, Netherlands.
Ries GrommenMSD Animal Health, Wim de Körverstraat 35, Boxmeer, Netherlands.
C Coral Domínguez-MedinaDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC Location University of Amsterdam, Amsterdam, Netherlands.ORCID 0000-0002-6071-9995
Irene M SchimmelElectron Microscopy Center Amsterdam, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands.ORCID 0009-0008-6197-9861
Nicole N van der WelElectron Microscopy Center Amsterdam, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands.ORCID 0000-0001-6392-3417
Cameron W KennerDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, KY, USA.
Christian HeissComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.ORCID 0000-0003-1118-8953
Parastoo AzadiComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.ORCID 0000-0002-6166-9432
Li TanComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.ORCID 0000-0003-3873-423X
Jeroen D C CodéeLeiden Institute of Chemistry, Leiden University, Leiden, Netherlands.ORCID 0000-0003-3531-2138
Arjan StegemanDepartment of Population Health Sciences, Division Farm Animal Health, Utrecht University, Utrecht, Netherlands.ORCID 0000-0003-4361-3846
Constance SchultszDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC Location University of Amsterdam, Amsterdam, Netherlands.
Lindert BenedictusDepartment of Population Health Sciences, Division Farm Animal Health, Utrecht University, Utrecht, Netherlands.ORCID 0000-0001-7605-2710
Nina M van SorgeDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC Location University of Amsterdam, Amsterdam, Netherlands.ORCID 0000-0002-2695-5863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, BacterialPolysaccharidesStreptococcal InfectionsStreptococcus suisZoonosesAnimalsGlycosyltransferasesHumansPolysaccharides, BacterialSwineAntibodies, BacterialGlycosyltransferasesPolysaccharidesPolysaccharides, Bacterial

Identifiers

PMID41880495
PMCPMC13015895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.