Evidence map›Paper›PMID 41880431›Full record

ArticleArquivos brasileiros de cardiologia2026

Implantation of Pacemakers in Patients with Chagas disease: A Case-Control Study of Associated Contextual Factors and Prognosis.

Sâmara Fernandes Leite, Maria Carmo Pereira Nunes, Cesar Augusto Taconeli, Mathaus Henrique Reis Silva, Dardiane Santos Cruz, Lea Campos Oliveira, Ester Cerdeira Sabino, Marco Paulo Tomáz Barbosa, Antonio Luis Pinho Ribeiro, Ariela Mota Ferreira and 1 more

Abstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sâmara Fernandes LeitePrograma de Pós Graduação em Ciências da Saúde, Universidade Estadual de Montes Claros (UNIMONTES), MG - Brasil.ORCID 0000-0001-7381-2454
Maria Carmo Pereira NunesDepartamento de Clínica Médica, Faculdade de Medicina, e Centro de Telessaúde e Serviço de Cardiologia e Cirurgia Cardiovascular, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG - Brasil.ORCID 0000-0001-8801-1828
Cesar Augusto TaconeliDepartamento de Estatística, Universidade Federal do Paraná, Curitiba, PR - Brasil.ORCID 0000-0002-3485-400X
Mathaus Henrique Reis SilvaPrograma de Pós Graduação em Ciências da Saúde, Universidade Estadual de Montes Claros (UNIMONTES), MG - Brasil.ORCID 0009-0009-9289-7014
Dardiane Santos CruzPrograma de Pós Graduação em Ciências da Saúde, Universidade Estadual de Montes Claros (UNIMONTES), MG - Brasil.ORCID 0000-0003-0157-3006
Lea Campos OliveiraInstituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo - USP,São Paulo, SP - Brasil.ORCID 0000-0002-7380-7548
Ester Cerdeira SabinoInstituto de Medicina Tropical da Faculdade de Medicina da Universidade de São Paulo - USP,São Paulo, SP - Brasil.ORCID 0000-0003-2623-5126
Marco Paulo Tomáz BarbosaServiço de Cardiologia e Cirurgia Cardiovascular, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG - Brasil.ORCID 0000-0001-5185-5365
Antonio Luis Pinho RibeiroDepartamento de Clínica Médica, Faculdade de Medicina, e Centro de Telessaúde e Serviço de Cardiologia e Cirurgia Cardiovascular, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG - Brasil.ORCID 0000-0002-2740-0042
Ariela Mota FerreiraPrograma de Pós Graduação em Ciências da Saúde, Universidade Estadual de Montes Claros (UNIMONTES), MG - Brasil.ORCID 0000-0002-2315-5318
Desirée Sant'Ana HaikalPrograma de Pós Graduação em Ciências da Saúde, Universidade Estadual de Montes Claros (UNIMONTES), MG - Brasil.ORCID 0000-0002-0331-0747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic Chagas cardiomyopathy (CCC) is the most severe manifestation of Chagas disease and may present with bradyarrhythmias requiring pacemaker (PM) implantation.

objective1. To identify contextual factors associated with PM implantation among individuals with CCC. 2. To assess the prognosis (death) in these groups over a 4-year follow-up period.

method1. Nested case-control study within the SaMi-Trop cohort. We matched cases (patients with CCC who had a PM implanted between waves 1 and 2 of the study) with controls at a 1:3 ratio, considering equivalence in baseline cardiac severity. Independent variables related to the municipal context were considered. Binary logistic regression was conducted. 2. Survival analysis to evaluate the prognosis of these groups, adjusted for clinical variables (Cox regression), considering death as the outcome. Conclusions were based on a significance level of 5%.

resultsThe study included 46 cases and 138 controls. The odds of PM implantation were higher among individuals residing in municipalities with: larger population (odds ratio [OR]: 3.6; 95% confidence interval [CI]: 1.3 to 9.6), higher coverage of the Family Health Strategy (OR: 5.3; 95% CI: 1.8 to 15.8), and with a lower number of electrocardiographs per thousand inhabitants (OR: 2.6; 95% CI: 1.0 to 6.6). Considering 4 years of follow-up, death was observed in 32.6% of cases and 21.2% of controls. Only ejection fraction affected survival (relative risk: 7.2; 95% CI: 3.6 to 14.2).

conclusionContextual factors interfered with PM implantation. However, PM implantation did not influence death over 4 years of follow-up, which was associated only with ejection fraction.

Indexed as

BradycardiaChagas CardiomyopathyPacemaker, ArtificialAdultAgedBrazilCase-Control StudiesEpidemiologic MethodsFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRisk FactorsTime Factors

Identifiers

PMID41880431
PMCPMC13128191

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.