Observational studyPloS one2026
Ultrasound-derived tibia-fascia angle for noninvasive assessment of intracompartmental pressure in tibial plateau fractures.
Observational study in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
backgroundCurrent noninvasive diagnostics for acute compartment syndrome (ACS) lack clinical practicality and reliability. This study aimed to evaluate ultrasound-derived tibia-fascia angle (TFA) as a novel morphometric surrogate for intracompartmental pressure (ICP) assessment.
methodsIn this observational study, 105 patients with closed tibial plateau fractures were enrolled at a tertiary trauma center. TFA was bilaterally measured using B-mode ultrasound by blinded operators. Invasive ICP served as the reference standard. Correlations were analyzed via Spearman correlation analysis and multivariable linear regression, and diagnostic performance for high compartment pressure (HCP, ICP > 30 mmHg) was assessed using ROC analysis.
resultsΔTFA showed a significant linear correlation with ICP after adjustment for confounders (β = 1.74 mmHg/°, 95% CI: 1.07-2.41, Padj < 0.001) and a moderate monotonic association (ρ = 0.545, 95%CI: 0.395-0.667, P < 0.001). For detecting HCP, ΔTFA achieved an area under the receiver operating characteristic curve (AUC) of 0.716 (95% CI: 0.621-0.812), with 86.5% sensitivity and 52.9% specificity at the optimal cutoff (ΔTFA ≥ 4.9°).
conclusionΔTFA provides a rapid, operator-friendly method for noninvasive ICP estimation, demonstrating moderate diagnostic accuracy as a screening tool for HCP in tibial plateau fractures. Its integration into trauma workflows could enhance early risk stratification, particularly for high-energy fractures, though specificity limitations warrant complementary confirmatory tests.
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