Evidence map›Paper›PMID 41880102›Full record

ReviewJournal of racial and ethnic health disparities2026

The Association of Social Determinants of Health on Mortality among Adults with End-Stage Kidney Disease: a Systematic Review and Meta-Analysis.

Prince Agyapong, Lauren Longacre, Patti Brooks, Hossein Moradi Rekabdarkolaee, Surachat Ngorsuraches, Aine O'Connor, Semhar Michael, Brandon M Varilek

Abstract readReview
In one paragraph

Review in Journal of racial and ethnic health disparities, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Prince AgyapongMathematics and Statistics Department, South Dakota State University, Brookings, SD, 57007, USA.ORCID http://orcid.org/0009-0001-9087-7820
Lauren LongacreCollege of Nursing, University of Nebraska Medical Center, Omaha, NE, 68198, USA.ORCID http://orcid.org/0009-0004-6221-9021
Patti BrooksCollege of Business and Information Systems, Dakota State University, Madison, SD, 57042, USA.ORCID http://orcid.org/0000-0001-6548-3689
Hossein Moradi RekabdarkolaeeDepartment of Applied Statistics and Operations Research, Bowling Green State University, Bowling Green, OH, 43403, USA.ORCID http://orcid.org/0000-0003-3449-4953
Surachat NgorsurachesHarrison College of Pharmacy, Auburn University, Auburn, AL, 36849, USA.ORCID http://orcid.org/0000-0002-2327-224X
Aine O'ConnorLila D. Bunch Library, Belmont University, Nashville, TN, 37212, USA.ORCID http://orcid.org/0000-0002-6033-8869
Semhar MichaelMathematics and Statistics Department, South Dakota State University, Brookings, SD, 57007, USA.ORCID http://orcid.org/0000-0002-9501-9550
Brandon M VarilekCollege of Nursing, University of Nebraska Medical Center, Omaha, NE, 68198, USA. bvarilek@unmc.edu.ORCID http://orcid.org/0000-0001-9426-5453

Funding

AIM-AHEAD Coordinating Center - All Four CoresOT2OD032581 · OD · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI Paul Avillach, Bettina M. Beech · 2021 to 2026
$168.7M
National Institutes of Health Office of Data Science Strategy (US) 1OT2OD032581NIH HHS OT2 OD032581
6 · The paper itself

Abstract

RATIONALE/

objectiveSynthesize evidence from published studies on end-stage kidney disease (ESKD) mortality and determine associations between social determinants of health (SDOH) and ESKD mortality. STUDY

designThis PRISMA-guided study examined all published research across four electronic databases. STUDY POPULATIONS: Adults with ESKD living in the United States. SELECTION CRITERIA FOR STUDIES: Clinical trials, observational, cross-sectional, and prospective/retrospective cohort studies were considered if one or more of the five domains of SDOH were present in the analysis. EXTRACTION/ANALYSIS: Extraction was performed independently by two reviewers using a standardized form that captured study purpose and design, outcomes, SDOH domain, setting, participant characteristics, and description of results. A systematic review of all eligible studies was completed. A meta-analysis was conducted using the restricted maximum likelihood method for the random effects model to assess the association of SDOH with mortality. Subgroups were analyzed by SDOH domains.

results86 studies met inclusion for the systematic review which were categorized by SDOH domain. Meta-analysis showed that those with higher levels of education (pooled HR 0.83 [95% CI, 0.69 − 0.1.00]) and those living in urban areas (pHR 0.92 [0.88–0.96]) had lower mortality risk. People from various minoritized backgrounds (Black-pHR 0.89 [0.85–0.93]; Asian-pHR 0.59 [0.55–0.64]; and American Indian/Alaska Native-pHR 0.82 [0.77–0.88]) had lower mortality risk compared to White populations.

conclusionsSDOH have a significant impact on mortality outcomes in persons with ESKD. The reductions in mortality risk reveal a survival paradox where it appears that minoritized groups have improved survival outcomes, but they are diagnosed with ESKD earlier than White populations and live on dialysis longer. It is critical to conduct research to develop strategies to mitigate individual social needs. REGISTRATION: Registered at PROSPERO: CRD42023483453.

Indexed as

End-stage kidney diseaseMeta-analysisSocial determinants of healthSystematic review

Identifiers

PMID41880102
PMCPMC13043201

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.