Evidence map›Paper›PMID 41880100›Full record

ArticlePituitary2026

Prolactin measurements in a real-life setting: a population-based cohort study.

Christoffer Krogager, Jens Otto Lunde Jørgensen, Claus Højbjerg Gravholt, Kirstine Stochholm

Abstract read
In one paragraph

Article in Pituitary, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christoffer KrogagerDepartment of Internal Medicine, Regional Hospital Horsens, Horsens, Denmark. christoffer.krogager@rsyd.dk.ORCID http://orcid.org/0000-0002-9590-7398
Jens Otto Lunde JørgensenDepartment of Endocrinology, Aarhus University Hospital, Aarhus, Denmark.
Claus Højbjerg GravholtDepartment of Endocrinology, Aarhus University Hospital, Aarhus, Denmark.
Kirstine StochholmDepartment of Endocrinology, Aarhus University Hospital, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHyperprolactinemia is mainly due to pituitary disorders including prolactinomas but other causes including adverse drug reactions exist. This study aimed to assess the frequency and pattern of serum prolactin measurements in a population-wide cohort in Central Region Denmark (1.32 mill inhabitants) from 2011 to 2022.

methodsUsing the Central Denmark Region’s data warehouse, we identified all individuals who had at least one prolactin measurement in the study period.

resultsWe identified 84,145 individuals who had at least one measurement of prolactin. Among these, 17,008 (20.3%) had at least one measurement of elevated prolactin corresponding to an incidence of 107 per 100.000 person-years. Hyperprolactinemia, defined by at least two elevated prolactin concentrations, occurred in 5,810 individuals (73.9% female), with an incidence of 36.7 per 100.000 person-years. Only 12.7% of individuals with hyperprolactinemia were treated with dopamine agonists.

conclusionWe found a substantial number of repeated prolactin measurements, many of which did not seem to lead to clinical action. The findings support the need for guidelines for management of hyperprolactinemia to ensure proper utilization of health resources.

Indexed as

HyperprolactinemiaProlactinAdultAgedCohort StudiesDenmarkDopamine AgonistsFemaleHumansMaleMiddle AgedProlactinomaYoung AdultDopamine AgonistsProlactinHyperprolactinemiaProlactin

Identifiers

PMID41880100
PMCPMC13018033

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