Evidence map›Paper›PMID 41879873›Full record

ReviewMikrochimica acta2026

Innovative dual-mode colorimetric/fluorescent sensors based on transition metal nanozymes: mechanisms, applications, and future perspectives.

Feiyan Yang, Dongxue Liu, Hongkun Lin, Hui Zhang, Ping Zhang, Chen Li, Jing Dong, Shanshan An, Fei Ren, Xiuhong Ge and 11 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Feiyan Yang *Public Health School, Mudanjiang Medical University, Mudanjiang, China.
Dongxue LiuPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Hongkun Lin *Public Health School, Mudanjiang Medical University, Mudanjiang, China.
Hui ZhangPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Ping ZhangPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Chen LiPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Jing DongPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Shanshan AnPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Fei RenPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Xiuhong GePublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Lang ChengPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Feifei WangPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Tianzi LiuPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Jiahan LiuPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Jiabo FuPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Furui TangPublic Health School, Mudanjiang Medical University, Mudanjiang, China.
Hongzhi PanCollaborative Research Center, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Lina ZouAffiliated Hongqi Hospital, Mudanjiang Medical University, Mudanjiang, China.
Xiaowei MaAffiliated Hongqi Hospital, Mudanjiang Medical University, Mudanjiang, China. xiaowei6054@163.com.
Hongkun MaPublic Health School, Mudanjiang Medical University, Mudanjiang, China. mahongkunmdjmu@163.com.
Shengzhong RongPublic Health School, Mudanjiang Medical University, Mudanjiang, China. sz_rong@yeah.net.

Funding

Foundation for Huoju Plan Research of Mudanjiang Medical University 2022-MYHJ-014Natural Science Foundation of Heilongjiang Province LH2023H054The Fundamental Research Funds for the Universities of Heilongjiang Province 2022-KYYWFMY-0712The National Natural Science Foundation of China 82574099Youth the Science and Technology Talents Team Project of Chunyan Plan of Heilongjiang Province CYQN24028
6 · The paper itself

Abstract

Transition metal nanozymes have emerged as promising alternatives to natural enzymes due to their exceptional catalytic activity, tunable physicochemical properties, and robust stability. In recent years, the integration of colorimetric and fluorescent sensing modalities into a single platform has garnered significant attention, offering complementary advantages in sensitivity, accuracy, and practical applicability. This comprehensive review systematically summarizes the latest advances in colorimetric/fluorescent dual-mode sensors based on transition metal nanozymes. We highlight their versatile applications in detecting heavy metals, foodborne pathogens, mycotoxins, organophosphorus pesticides, antibiotics, biomolecules, and tumor markers. Furthermore, the review elucidates the catalytic mechanisms of various nanozymes, including oxidase-like, peroxidase-like, catalase-like, and superoxide dismutase-like activities, and discusses their design principles and synthesis strategies. Finally, we address the current challenges—such as environmental susceptibility and limited integration with portable devices—and propose future directions for enhancing nanozyme performance and expanding their real-world applications. This work aims to provide valuable insights and a foundational reference for researchers in the fields of biosensing, environmental monitoring, and food safety.

Indexed as

Biosensing TechniquesColorimetryFluorescent DyesMetal NanoparticlesTransition ElementsCatalysisHumansSpectrometry, FluorescenceFluorescent DyesTransition ElementsColorimetric detectionDual-mode sensorsFluorescence detectionTransition metal nanozymes

Identifiers

PMID41879873

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.