ArticleJACC. Case reports2026
Transcatheter Paravalvular Leak Closure Using Valve Frame Access.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe a step-by-step approach to transcatheter paravalvular leak (PVL) closure after transcatheter aortic valve replacement (TAVR) using frame-based access through a self-expanding valve. KEY STEPS: An 85-year-old man with a 34-mm Evolut FX+ TAVR valve developed worsening heart failure. Multimodality imaging showed moderate to severe PVL with adverse left ventricular remodeling. Preprocedural computed tomography localized a dominant jet aligned with a misaligned diamond-shaped cell of the Evolut valve. A closure device was delivered through this cell, markedly reducing PVL. POTENTIAL PITFALLS: Inadequate multimodality imaging may cause incorrect leak localization, device malposition, or longer procedures. Challenges include crossing the PVL tract within the valve frame and avoiding leaflet interference. Balloon postdilation may fail in heavily calcified annuli and adds risk. TAKE-HOME MESSAGES: Severe calcification and commissural misalignment can limit balloon postdilation. Careful computed tomography planning can identify favorable frame-based access (eg, Evolut FX+ diamond cell) and enable effective PVL closure in selected anatomies.
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