Evidence map›Paper›PMID 41879592›Full record

ArticleJACC. Case reports2026

Giant Isolated Congenital Left Atrial Appendage Aneurysm Complicated by Thrombus: Multimodality Imaging Assessment.

José Martín Alanís-Naranjo, Gabriela Meléndez-Ramírez, Regina de la Mora-Cervantes, José Antonio Arias-Godínez, Aloha Meave-González, Silvia Jiménez-Becerra, Sergio Alfonso Patrón-Chi

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

José Martín Alanís-NaranjoCardiovascular Imaging Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Gabriela Meléndez-RamírezCardiac Magnetic Resonance Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico; Cardiovascular Imaging Department, Centro Médico Nacional 20 de Noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mexico City, Mexico.
Regina de la Mora-CervantesCardiac Computed Tomography Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
José Antonio Arias-GodínezEchocardiography Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Aloha Meave-GonzálezCardiac Magnetic Resonance Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Silvia Jiménez-BecerraPathology Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Sergio Alfonso Patrón-ChiCardiac Magnetic Resonance Department, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico. Electronic address: drsergiopatron@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft atrial appendage aneurysm (LAAA) is a rare cardiac malformation; giant forms of LAAA complicated by thrombus are exceptionally uncommon. CASE SUMMARY: A 36-year-old woman with atrial flutter, palpitations, and dyspnea was evaluated after chest radiography showed cardiomegaly and computed tomography revealed a mediastinal mass. Cardiac magnetic resonance confirmed a giant LAAA measuring 11 × 6 × 1 cm with a thrombus measuring 21 × 25 × 24 mm, producing a mass effect and contacting the mid-left anterior descending artery. Surgical resection was performed, with remission of atrial flutter, resolution of symptoms, and clinical stability at 6-month follow-up. DISCUSSION: LAAA is linked to arrhythmia, embolic events, and compression. Multimodality imaging defines anatomy and thrombus, while surgery is the treatment in complicated cases. TAKE-HOME MESSAGES: LAAA carries risks of arrhythmia, thromboembolism, and compression. Multimodality imaging enables diagnosis and thrombus detection. Surgery provides symptom relief, arrhythmia remission, and prevention of complications.

Indexed as

aneurysmcardiac computed tomographycardiac magnetic resonanceleft atrial appendageleft atrial massmultimodality imaging

Identifiers

PMID41879592
PMCPMC13130894

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.