Evidence map›Paper›PMID 41878704›Full record

ArticleJCEM case reports2026

Treating microsatellite unstable metastatic parathyroid carcinoma with anti-PD1 therapy.

Borna Amir-Kabirian, Radhwan AlRubaye, Benjamin Cadle, Daniel Mais, Zakaria Sibai, Rebecca Redman

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JCEM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Borna Amir-KabirianDepartment of Medicine, Division of Medical Oncology and Hematology, University of Louisville, 529 S Jackston St, Louisville, KY 40202, USA.ORCID https://orcid.org/0009-0002-8401-4719
Radhwan AlRubayeDepartment of Medicine, Division of Endocrinology, University of Louisville, 550 S Jackson St, Louisville, KY 40202, USA.
Benjamin CadleUniversity of Louisville School of Medicine, 323 E Chestnut Street, Louisville, KY 40202, USA.
Daniel MaisDepartment of Pathology, University of Louisville, #23 E Chestnut Street, Louisville, KY 40202, USA.
Zakaria SibaiDepartment of Medicine, Division of Endocrinology, University of Louisville, 550 S Jackson St, Louisville, KY 40202, USA.
Rebecca RedmanDepartment of Medicine, Division of Medical Oncology and Hematology, University of Louisville, 529 S Jackston St, Louisville, KY 40202, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid carcinoma (PC) is a rare endocrine malignancy that often clinically mimics primary hyperparathyroidism (PHPT) caused by parathyroid adenoma or hyperplasia. Complete resection of malignancy is the only curative treatment, and to date, there is no effective systemic therapy for advanced disease. A 60-year-old woman was referred for evaluation of hypercalcemia. Laboratory studies were consistent with PHPT. She underwent right superior parathyroidectomy, and pathology revealed PC with lymphovascular invasion. Postoperatively, calcium and parathyroid hormone levels normalized but recurred 6 months later. Imaging identified metastatic PC. Somatic genetic testing revealed a MutS homolog 2 (

Indexed as

immune checkpoint inhibitormicrosatellite instabilityparathyroid carcinoma

Identifiers

PMID41878704
PMCPMC13008480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.