Evidence map›Paper›PMID 41878672›Full record

SynthesisTransplant international : official journal of the European Society for Organ Transplantation2026

Impact of Vascular Anastomosis Time on Kidney Transplant Outcomes - A Systematic Review.

Khaled Sayah, Henry Burt, Yizi Zheng, Taina Lee, Lawrence Yuen, Christopher Nahm, Jinna Yao, Wai Lim, Germaine Wong, Leonard Lee and 2 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Transplant international : official journal of the European Society for Organ Transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Impact of Vascular Anastomosis Time on Kidney Transplant Outcomes - A Systematic Review.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Khaled SayahSchool of Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, USYD, Australia.
Henry BurtSchool of Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, USYD, Australia.
Yizi ZhengSchool of Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, USYD, Australia.
Taina LeeWestmead Hospital, Westmead, WMH, Australia.
Lawrence YuenWestmead Hospital, Westmead, WMH, Australia.
Christopher NahmSchool of Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, USYD, Australia.
Jinna YaoWestmead Hospital, Westmead, WMH, Australia.
Wai LimSchool of Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, USYD, Australia.
Germaine WongSchool of Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, USYD, Australia.
Leonard LeeSchool of Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, USYD, Australia.
Ahmer HameedSchool of Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, USYD, Australia.
Henry PleassSchool of Medicine, Faculty of Medicine and Health, The University of Sydney, Sydney, USYD, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anastomotic time (AT), also termed second warm ischaemic time (SWIT), is a potentially important intraoperative factor in kidney transplantation, yet its impact on outcomes has not been systematically synthesised. We conducted a systematic review to examine the association between AT and delayed graft function (DGF), graft survival, and patient survival. Cochrane, Embase, and Medline were searched to 21 July 2025. Nine retrospective cohort studies comprising 155,523 transplants were included. Across all donor types, longer AT was consistently associated with higher rates of DGF within individual studies. Several studies also reported poorer 1- and 5-year graft survival with prolonged AT, while findings for patient survival were equivocal. However, substantial heterogeneity across studies, including donor type, AT definitions, outcome reporting, and incomplete adjustment for key confounders, precluded formal meta-analysis. None of the included studies consistently adjusted for major determinants of graft outcomes. These findings suggest a potential link between prolonged AT and adverse graft outcomes, but high-quality prospective studies with standardised reporting and confounder adjustment are required before AT can be considered an independent determinant of transplant outcomes. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier PROSPERO CRD42024549222.

Indexed as

Kidney TransplantationWarm IschemiaAnastomosis, SurgicalDelayed Graft FunctionGraft SurvivalHumansRetrospective StudiesTime FactorsTreatment Outcomeanastomosissecond warm ischaemic timesurgicalsurgical anastomosistransplant

Identifiers

PMID41878672
PMCPMC13006796

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.