ArticleInternational journal of general medicine2026
Clinical Screening and Factors Influencing Growing Pain in Children with Recurrent Lower Limb Pain: A Controlled Study on Symptom Assessment and Motor Load.
Article in International journal of general medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Risk factors associated with growth pain disorder in children: a systematic review and meta-analysis.Frontiers in pediatrics · 2026Review
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Authors and funding
2 authors.
Funding
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Abstract
Background: Recurrent lower limb pain (RLLP) is common in children, with growth pain (GP) lacking objective diagnostic criteria and often confused with organic pain. This study aims to compare clinical characteristics and post-exercise pain responses among children with GP, disease controls (DC), and healthy controls (HC). Methods: This prospective controlled study (January 2023-March 2025) enrolled 201 children aged 3-12 years (67 in the GP group, 62 in the DC group, and 72 in the HC group). Baseline data and standardized symptom assessments were collected, followed by a unified standardized jump rope exercise load test. Immediate and 24-hour post-exercise visual analog scale (VAS) pain dynamics were compared. Results: The proportion of GP group participants with bone age advancement ≥3 months (44.78%) was significantly higher than in the DC group (16.13%) and HC group (25.00%, P < 0.001). Symptomatically, the GP group predominantly experienced evening/nighttime soreness (89.55%) and short-duration pain (median 31 minutes), whereas the DC group more commonly reported morning stabbing pain (40.32%) and long-duration pain (median 79 minutes) (P < 0.001). Exercise stress testing revealed that pain intensified post-exercise in both GP and DC groups. However, the DC group exhibited a "sharp increase-rapid decline" pattern, whereas the GP group showed a slower recovery. Conclusion: Standardized exercise stress testing reveals distinct pain recovery patterns, serving as a valuable supplement to symptom screening. Nevertheless, its efficacy in directly differentiating GP from organic diseases remains limited. Future research should integrate additional indicators to optimize diagnostic strategies.
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