Evidence map›Paper›PMID 41878592›Full record

ArticleOxford medical case reports2026

Paroxysmal motor signs in multiple sclerosis: an illustrative videotaped case.

Ghita Lahmam, Asmae Sikkal, Hajar Khattab, Kamal Haddouali, Salma Bellakhdar, Bouchra El Moutawakil, Mohamed Abdoh Rafai, Hicham El Otmani

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ghita LahmamHassan II University of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Rue Tarik Ibn Ziad, Casablanca, Casablanca-Settat 20100, Morocco.ORCID https://orcid.org/0009-0002-3492-9806
Asmae SikkalHassan II University of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Rue Tarik Ibn Ziad, Casablanca, Casablanca-Settat 20100, Morocco.ORCID https://orcid.org/0009-0009-3774-5704
Hajar KhattabHassan II University of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Rue Tarik Ibn Ziad, Casablanca, Casablanca-Settat 20100, Morocco.ORCID https://orcid.org/0000-0001-8124-7651
Kamal HaddoualiHassan II University of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Rue Tarik Ibn Ziad, Casablanca, Casablanca-Settat 20100, Morocco.ORCID https://orcid.org/0009-0002-5656-8669
Salma BellakhdarHassan II University of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Rue Tarik Ibn Ziad, Casablanca, Casablanca-Settat 20100, Morocco.ORCID https://orcid.org/0000-0002-4580-2774
Bouchra El MoutawakilHassan II University of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Rue Tarik Ibn Ziad, Casablanca, Casablanca-Settat 20100, Morocco.ORCID https://orcid.org/0009-0004-1208-8449
Mohamed Abdoh RafaiHassan II University of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Rue Tarik Ibn Ziad, Casablanca, Casablanca-Settat 20100, Morocco.ORCID https://orcid.org/0000-0002-4342-7499
Hicham El OtmaniHassan II University of Casablanca, Faculty of Medicine and Pharmacy of Casablanca, Rue Tarik Ibn Ziad, Casablanca, Casablanca-Settat 20100, Morocco.ORCID https://orcid.org/0000-0003-0870-1808

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) presents with a wide spectrum of neurological manifestations, among which paroxysmal motor phenomena remain a diagnostic and therapeutic challenge. We report the case of a 29-year-old male diagnosed with relapsing-remitting MS (RRMS) who exhibited episodes of paroxysmal dystonia, dysarthria-ataxia, and ptosis. Brain MRI revealed multiple demyelinating plaques, including a contrast-enhancing lesion in the right midbrain, which provides an anatomical correlation with the patient's neurological manifestation. The dystonic movements resolved with corticosteroid therapy, while symptomatic management with carbamazepine was required for dysarthria-ataxia. Ocrelizumab has been proposed as a long-term disease-modifying treatment. This case highlights the importance of recognizing paroxysmal motor signs in MS for early diagnosis and tailored management, despite their elusive pathogenesis.

Indexed as

ataxiaChoreo-dystoniadysarthriamultiple sclerosisparoxysmal

Identifiers

PMID41878592
PMCPMC13007868

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.