Evidence map›Paper›PMID 41877902›Full record

ReviewInfection and drug resistance2026

From Antibiotic Resistance to Bacterial Vaccines: A New Approach to Controlling Resistant Bacterial Infections.

Feiyang Xiong, Xiayi Fang, Yanping Lu, Wenliang Lv

Abstract readReview
In one paragraph

Review in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Feiyang Xiong *Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Xiayi Fang *Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Yanping LuDepartment of Hepatology, Shenzhen Bao'an District Traditional Chinese Medicine Hospital, Shenzhen, People's Republic of China.
Wenliang LvDepartment of Infection, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is one of the major threats to global health, with a complex and diverse underlying mechanism. Vaccines reduce the dependence on antimicrobial agents by preventing and treating bacterial and viral infections, as well as secondary infections caused by both, thereby lowering the risk of AMR. Unlike traditional antibiotics, bacterial vaccines trigger a long-lasting immune response that not only prevents bacterial infections but also inhibits the spread of resistant strains. They show significant advantages in reducing antibiotic use and lowering resistance risks. However, the development of bacterial vaccines faces several challenges, including the diversity of bacterial antigens, rapid evolution, and the difficulty of achieving broad-spectrum immune protection. Despite these challenges, advancements in vaccine technology and the optimization of delivery systems are making the application prospects of bacterial vaccines in combating resistant strains increasingly promising. We sequentially discuss resistance mechanisms, existing and emerging vaccine platforms, enabling technologies, and future perspectives.

Indexed as

antimicrobial resistancebacterial infectionsbacterial vaccineschallengestechnology

Identifiers

PMID41877902
PMCPMC13007677

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.