ArticleContact dermatitis2026
Is There an Allergy to Pure Metallic Gold Micro-Particles?-An Epicutaneous Study of Gold Micro-Particles, Gold Thiosulphate, and Placebo.
Article in Contact dermatitis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Patch Test Reactions to Dental Materials: A Retrospective Single-Centre Study.Contact dermatitis · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies investigating gold allergy have used gold thiosulphate (GCST) rather than pure gold, reporting an incidence up to 30%.
objectivesAs it is unclear whether these reactions are due to ions from pure gold or solely to ions from gold salts, this study aimed to determine whether an allergy to pure gold itself exists. MATERIALS AND
methodsSixty patients with cutaneous allergic reactions participated in the study. A standard epicutaneous test was performed with both a test chamber with pure gold micro-particles (20-40 μm in diameter) in petrolatum and the GST, which is part of the standard 'Thin Layer Rapid Use Epicutaneous Patch (T.R.U.E.) Test'.
resultsNone of the patients reacted to the gold micro-particles, while thirteen reacted to GST.
conclusionsThe study did not elicit any allergic reaction to the gold micro-particles. These findings confirmed clinical observations that allergy to gold salts is quite common but suggest that pure metallic gold is not an allergen.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.