Evidence map›Paper›PMID 41877328›Full record

ArticleBMJ open2026

Effect of home-based walking exercise and education on early functional recovery after lung cancer surgery: protocol for the WalkLung multicentre randomised controlled trial.

Yadi Zhang, Xiaoyan Liu, Xiuyang Shi, Puyang Feng, Yi Chen, Cheng Lei, Hongyu Zeng, Tingting Li, Ping Gui, Manli Li and 14 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Yadi ZhangDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.ORCID http://orcid.org/0009-0004-9182-3797
Xiaoyan LiuDepartment of Thoracic Surgery, Ya'an People's Hospital, Ya'an, Sichuan, China.
Xiuyang ShiDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Puyang FengDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Yi ChenDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Cheng LeiDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0003-1311-515X
Hongyu ZengDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Tingting LiDepartment of Health Management Center, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Ping GuiCentral Sterile Supply Department, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Manli LiDepartment of Thoracic Surgery, Ya'an People's Hospital, Ya'an, Sichuan, China.
Li WangDepartment of Thoracic Surgery, Ya'an People's Hospital, Ya'an, Sichuan, China.
Rong ZhangDepartment of Thoracic Surgery, Ya'an People's Hospital, Ya'an, Sichuan, China.
Yu HeDepartment of Thoracic Surgery, Ya'an People's Hospital, Ya'an, Sichuan, China.
Yanmei ChenDepartment of Cardiothoracic Surgery, Zigong First People's Hospital, Zigong, Sichuan, China.
Dequn ChenDepartment of Cardiothoracic Surgery, Zigong First People's Hospital, Zigong, Sichuan, China.
Yuanqiang ZhangDepartment of Cardiothoracic Surgery, Zigong First People's Hospital, Zigong, Sichuan, China.
Jia LiaoDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Xing WeiDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0002-3035-5633
Bo TianDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0003-1283-3045
Xiaoqin LiuDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Qiang LiDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Qiuling ShiDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0003-0660-3809
Xiaokang ChenDepartment of Cardiothoracic Surgery, Zigong First People's Hospital, Zigong, Sichuan, China daiwei@sichuancancer.org 1256554839@qq.com.
Wei DaiDepartment of Thoracic Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China daiwei@sichuancancer.org 1256554839@qq.com.ORCID http://orcid.org/0000-0003-1650-1590

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWalking, as a simple, low-cost and easily implemented form of exercise, offers multiple health advantages. The WalkLung trial aims to evaluate the efficacy of a home-based walking exercise and education intervention in promoting early functional recovery after lung cancer surgery. METHODS AND ANALYSIS: WalkLung is a multicentre, parallel-group, randomised controlled trial conducted at three hospitals in China, with stratification by study centre. A total of 116 patients with postoperative lung cancer will be randomised in a 1:1 ratio to either the intervention group (home-based walking exercise and education for 4 weeks) or the control group (usual care). The primary outcome is the longitudinal walking difficulty score during the 4-week postdischarge, measured by the validated perioperative symptom assessment for lung surgery scale (0-10 scale), assessed at discharge and weekly for 4 weeks. Secondary outcomes are the 6-min walk test, pulmonary function, complications, physical activity level, quality of life, social functioning, exercise adherence and adverse events. Long-term outcomes (up to 6 months) will be analysed and reported separately. All analyses will use an intention-to-treat approach, with outcome measures analysed as appropriate using generalised estimating equations for repeated measures, and t-tests or χ ETHICS AND DISSEMINATION: Ethical approval was obtained from the Ethics Committee for Medical Research and New Medical Technology of Sichuan Cancer Hospital (No. SCCHEC-02-2025-091) and all participating subcentres. Written informed consent will be obtained from all participants. The manuscript is based on protocol V.1.0 (2 January 2025). The study findings will be disseminated through peer-reviewed journal publications and conference presentations. TRIAL REGISTRATION NUMBER: ChiCTR2500103081.

Indexed as

Exercise TherapyLung NeoplasmsPatient Education as TopicRecovery of FunctionWalkingChinaFemaleHumansMulticenter Studies as TopicQuality of LifeRandomized Controlled Trials as TopicWalk TestExercisePatient Reported Outcome MeasuresRandomized Controlled TrialRespiratory tract tumoursThoracic surgery

Identifiers

PMID41877328
PMCPMC13034199

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.