Evidence map›Paper›PMID 41877264›Full record

ArticleBioPsychoSocial medicine2026

Anxious Depressive Attack (ADA) -its prevalence and clinical implication.

Hisanobu Kaiya, Shota Noda, Satomi Matsumoto, Yojiro Sakai, Takeshi Otowa, Tsukasa Sasaki, Fusaka Minami

Abstract read
In one paragraph

Article in BioPsychoSocial medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Anxious-depressive attack-A clinical state with intrusive rumination.PCN reports : psychiatry and clinical neurosciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hisanobu KaiyaPanic Disorder Research Center, Warakukai Medical Corporation, 3-9-18 Akasaka, Minato-ku, Tokyo, 107-0052, Japan. kai@fuanclinic.com.ORCID http://orcid.org/0000-0002-8701-5015
Shota NodaAkasaka Clinic, Warakukai Medical Corporation, 3-9-18 Akasaka, Minato-ku, Tokyo, 107-0052, Japan.
Satomi MatsumotoAkasaka Clinic, Warakukai Medical Corporation, 3-9-18 Akasaka, Minato-ku, Tokyo, 107-0052, Japan.
Yojiro SakaiYokohama Clinic, Warakukai Medical Corporation, 1-2-10 Kitasaiwai, Nishi-ku, Yokohama, 220-0004, Japan.
Takeshi OtowaDepartment of Psychiatry, Teikyo University School of Medicine, 2-11-1Kaga, Itabashi-ku, Tokyo, 173-8605, Japan.
Tsukasa SasakiLaboratory of Health Education, Graduate School of Education, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
Fusaka MinamiAkasaka Clinic, Warakukai Medical Corporation, 3-9-18 Akasaka, Minato-ku, Tokyo, 107-0052, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnxious-Depressive Attack (ADA) is one of the three types of anxiety attacks originally described by Freud. ADA is characterized by the sudden onset of intense anxiety, immediately followed by intrusive ruminations. These intrusive thoughts, often centered on past regrets or future worries, cause significant psychological distress. Some individuals respond to these episodes with maladaptive or impulsive coping behaviors. This study aimed to investigate the prevalence of ADA among new patients at an anxiety disorder specialty clinic and to examine the associated psychiatric and psychological characteristics.

methodsNew patients (N = 286) presenting to an anxiety disorder clinic in Tokyo were assessed for the presence of ADA independently by a psychiatrist and Certified Public Psychologists (Japan), based on predefined diagnostic criteria. Axis I and Axis II diagnoses were established using the Japanese version of the Mini-International Neuropsychiatric Interview (MINI) and the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II), respectively. Histories of early separation or abuse were assessed using structured questionnaires. Psychological assessments of anxiety, depression, social anxiety, stress, and rejection sensitivity (RS) were conducted. Structural equation modeling (SEM) was performed to examine relationships among these variables.

resultsThe lifetime prevalence of ADA was 21.68%. ADA was observed across 16 Axis I disorders and 6 Axis II personality disorders. Compared with patients without ADA, those with ADA exhibited significantly higher scores on all psychological measures. SEM demonstrated that both RS and depressive symptoms independently contributed to the occurrence of ADA.

conclusionADA was found across a wide range of psychiatric disorders characterized by heightened RS. These findings suggest that ADA may be associated with increased clinical complexity. Active screening for ADA in clinical practice may facilitate early identification and more appropriate intervention strategies.

Indexed as

Anxious depressive attackAtypical depressionImpulsive copingRejection sensitivityTransdiagnostic

Identifiers

PMID41877264
PMCPMC13137476

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.