Evidence map›Paper›PMID 41877098›Full record

SynthesisBMC cancer2026

Effect of healthcare professional-delivered health literacy interventions on patient reported outcomes in cancer patients - a systematic review.

Malui Katrischa Frei, Gieri Cathomas, Monica Fliedner, Martin D Berger, Beatrice Minder, Marie-Luise Fontana, Alexander Wünsch

Abstract readSystematic Review
In one paragraph

Synthesis in BMC cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Malui Katrischa FreiDepartment of Health Psychology and Behavioral Medicine, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0009-0001-4988-5079
Gieri CathomasInstitute of Tissue Medicine and Pathology, Clinical Pathology, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-1276-4940
Monica FliednerDepartment of Oncology, University Center for Palliative Care, Inselspital, University Hospital Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-9018-7571
Martin D BergerDepartment of Medical Oncology, University Hospital Inselspital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0001-9224-7104
Beatrice MinderPublic Health and Primary Care Library, University Library of Bern, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-1345-2594
Marie-Luise Fontana *Department of Medical Oncology, Psycho-Oncology Unit, University Hospital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0009-0008-2545-980X
Alexander Wünsch *Department of Medical Oncology, Psycho-Oncology Unit, University Hospital, University of Bern, Bern, Switzerland. alexander.wuensch@insel.ch.ORCID http://orcid.org/0000-0003-1972-7093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer impairs quality of life (QoL) and mental wellbeing and other patient-reported outcomes (PROs). Health literacy (HL) in cancer patients can be an intermediary factor and can improve PROs. For this reason, the aim of this systematic review is to identify HL interventions delivered by healthcare professionals (HCPs) that have an impact on PROs.

methodsWe carried out a comprehensive literature search on 1 December 2023 across nine databases and included studies 1) with HL interventions delivered through HCPs aiming to have an effect on HL, HL-related outcomes, anxiety, depression, self-efficacy (SE) or QoL, 2) with adult patients ≥ 18 years with cancer, 3) written in English or German, and 4) with full-text availability. Two raters conducted screening, data extraction and quality assessment. We applied the Mixed Methods Appraisal Tool (MMAT) for study quality. We analyzed data and narratively synthesized.

resultsThirty-one studies were included in the review. We categorized intervention types in education, support management, consultation, and decision aid.Interventions were administered mostly by physicians or nurses. HL, knowledge, and adherence to treatment was significantly improved across all types of interventions, while only education and management support interventions showed additional impact on QoL, anxiety, and depression through allowing patients with autonomy and independence but with guidance of HCPs. No effect on PROs was detected in studies focusing on consultation and decision aids, where patients lacked guidance.

conclusionsThis review highlights the importance of tailored HL interventions focusing on PROs through education and support management by guidance of HCPs and the need of interprofessional teams to enhance PROs.

trial registrationThe protocol of this systematic review was prospectively registered on PROSPERO (CRD42023482254).

Indexed as

Health LiteracyHealth PersonnelNeoplasmsPatient Reported Outcome MeasuresHumansQuality of LifeAnxietyCancerDepressionHealthcare professionalsHealth literacyHealth literacy interventionsQuality of lifeSelf-efficacy

Identifiers

PMID41877098
PMCPMC13141578

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.