ArticleScientific reports2026
Combining graphlets and random walks for capturing complex network topology.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Random-walk-based methods are widely used for network embedding and downstream learning tasks, yet it remains unclear which aspects of network topology they capture and which they ignore. This is a critical limitation in networks where node function depends not only on direct connectivity, but also on higher-order structural patterns. To address this gap, we introduce orbit adjacency, a graphlet-based descriptor that measures how often pairs of nodes co-occur in specific symmetric positions within small induced subgraphs. Using orbit adjacency, we provide a theoretical analysis showing that random walks capture only a subset of local wiring patterns and inherently combine those they do capture, thereby obscuring structurally informative signals. We empirically demonstrate that these limitations hinder the ability of random-walk-based embeddings to capture topology-function relationships across 40 real-world networks from social, technological, and biological domains using a node-label prediction task. Our results show that orbit adjacency-based representations consistently outperform random-walk-based methods, highlighting the importance of explicitly modelling higher-order structural patterns. Overall, this work provides a unified framework for understanding the topology captured by random walks and establishes orbit adjacency as an effective alternative for topology-aware network analysis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.