Evidence map›Paper›PMID 41876766›Full record

ArticleScientific reports2026

Combining graphlets and random walks for capturing complex network topology.

Sam F L Windels, Noël Malod-Dognin, Nataša Pržulj

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sam F L WindelsMBZ University of Artificial Intelligence, SE45 05, Abu Dhabi, UAE.
Noël Malod-DogninMBZ University of Artificial Intelligence, SE45 05, Abu Dhabi, UAE.
Nataša PržuljMBZ University of Artificial Intelligence, SE45 05, Abu Dhabi, UAE. natasa.przulj@mbzuai.ac.ae.

Funding

European Research Council (ERC) Consolidator Grant [770827]Juan de la Cierva postdoctoral fellowship JDC2023- 004889-C
6 · The paper itself

Abstract

Random-walk-based methods are widely used for network embedding and downstream learning tasks, yet it remains unclear which aspects of network topology they capture and which they ignore. This is a critical limitation in networks where node function depends not only on direct connectivity, but also on higher-order structural patterns. To address this gap, we introduce orbit adjacency, a graphlet-based descriptor that measures how often pairs of nodes co-occur in specific symmetric positions within small induced subgraphs. Using orbit adjacency, we provide a theoretical analysis showing that random walks capture only a subset of local wiring patterns and inherently combine those they do capture, thereby obscuring structurally informative signals. We empirically demonstrate that these limitations hinder the ability of random-walk-based embeddings to capture topology-function relationships across 40 real-world networks from social, technological, and biological domains using a node-label prediction task. Our results show that orbit adjacency-based representations consistently outperform random-walk-based methods, highlighting the importance of explicitly modelling higher-order structural patterns. Overall, this work provides a unified framework for understanding the topology captured by random walks and establishes orbit adjacency as an effective alternative for topology-aware network analysis.

Identifiers

PMID41876766
PMCPMC13168442

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.