Evidence map›Paper›PMID 41876676›Full record

ArticleEye (London, England)2026

The Royal College of Ophthalmologists National Ophthalmology Database age-related macular degeneration (AMD) audit: report 1, associations with socio-economic deprivation in neovascular AMD.

Riddhi Shenoy, Mable T Monachan, Marta Gruszka-Goh, Martin McKibbin

Abstract read
In one paragraph

Article in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Riddhi ShenoyUlverscroft Eye Unit, University of Leicester, Leicester, United Kingdom. sr670@leicester.ac.uk.ORCID http://orcid.org/0000-0001-8118-9009
Mable T MonachanGloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.ORCID http://orcid.org/0009-0009-9646-6019
Marta Gruszka-GohGloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.ORCID http://orcid.org/0009-0002-8742-9135
Martin McKibbinThe Royal College of Ophthalmologists' National Ophthalmology Database Audit, London, UK.ORCID http://orcid.org/0000-0003-4388-243X

Funding

DH | National Institute for Health Research (NIHR) ACF-2023-11-004
6 · The paper itself

Abstract

backgroundEarly diagnosis and treatment of neovascular age-related macular degeneration (NvAMD) improve vision outcomes. This analysis investigates associations of English indices of multiple deprivation 2019 (IMD2019) with baseline characteristics, key care processes and visual acuity (VA) outcomes for NvAMD in the National Ophthalmology Database (NOD).

methodsEligible eyes started treatment for NvAMD in England between 01/04/2020 and 31/03/2023. Participating centres with ≥25 eyes with baseline VA and IMD2019 data were included.

resultsEligible for analysis were 48,583 eyes from 60 English centres. Between decile 1 (most deprived) and decile 10 (least deprived), median age at start of treatment ranged from 79 to 82 years and median baseline VA ranged from 56 to 60 ETDRS letters. After one year of treatment (-28 to +84 days), the median number of injections administered ranged from 7 to 8 across deciles. Loss to follow-up was observed in 13.7% eyes in decile 1, and 11.8% in decile 10. Median VA at 12 months ranged from 61 to 65 ETDRS letters across deciles. A "good" VA outcome (≥70 ETDRS letters) was achieved by 45.5% in decile 10, compared with 35.9% observed in decile 1 (p < 0.001). A "poor" VA outcome (≥10 ETDRS letter loss from baseline) occurred in 18.4% of eyes in decile 1 versus 14.5% in decile 10 (p < 0.001).

conclusionsPatients starting NHS-funded treatment in England for NvAMD and living in areas of higher socioeconomic deprivation were typically younger, had lower baseline acuity and achieved worse VA outcomes than those from lower deprivation areas, with little variation in treatment between the deciles.

Indexed as

OphthalmologistsOphthalmologyWet Macular DegenerationAgedAged, 80 and overAngiogenesis InhibitorsDatabases, FactualEnglandFemaleHumansIntravitreal InjectionsLow Socioeconomic StatusMaleRanibizumabSocieties, MedicalSocioeconomic Disparities in HealthAngiogenesis InhibitorsRanibizumab

Identifiers

PMID41876676
PMCPMC13161383

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.